survodutide [Ligand Id: 13383] activity data from GtoPdb

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  • GLP-1 receptor in Human [GtoPdb: 249] [UniProtKB: P43220]
  • GLP-1 receptor in Mouse [GtoPdb: 249] [UniProtKB: O35659]
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  • glucagon receptor in Human [GtoPdb: 251] [UniProtKB: P47871]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GLP-1 receptor in Human [GtoPdb: 249] [UniProtKB: P43220]
GtoPdb Determined using a cAMP assay in CHO-K1 cells expressing hGLPIR - 9.48 pEC50 0.33 nM EC50 Mol Metab (2022) 66: 101633 [PMID:36356832]
GLP-1 receptor in Mouse [GtoPdb: 249] [UniProtKB: O35659]
GtoPdb Dtermined using a cAMP assay in mouse MIN6 insulinoma cells - 9.44 pEC50 0.36 nM EC50 Mol Metab (2022) 66: 101633 [PMID:36356832]
glucagon receptor in Human [GtoPdb: 251] [UniProtKB: P47871]
GtoPdb Determined using a cAMP assay in CHO-K1 cells expressing hGCGR - 9.28 pEC50 0.52 nM EC50 Mol Metab (2022) 66: 101633 [PMID:36356832]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.