ChEMBL ligand: CHEMBL140979 (JTC-801)
δ receptor/Delta opioid receptor in Human [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143] There should be some charts here, you may need to enable JavaScript!
κ receptor/Kappa opioid receptor in Human [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145] There should be some charts here, you may need to enable JavaScript!
μ receptor/Mu opioid receptor in Human [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372] There should be some charts here, you may need to enable JavaScript!
NOP receptor/Nociceptin receptor in Human [ChEMBL: CHEMBL2014] [GtoPdb: 320] [UniProtKB: P41146] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
δ receptor/Delta opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL236] [GtoPdb: 317] [UniProtKB: P41143]
ChEMBL	Inhibition of [3H]naltrindole (0.55 nM) binding from human Opioid receptor delta 1 expressed in CHO-K1 cells.	B	5.06	pKi	8647.2	nM	Ki	J Med Chem (2000) 43: 4667-4677 [PMID:11101358]
ChEMBL	Binding affinity for opioid receptor type, human Opioid receptor delta 1 expressed in membrane homogenates of COS-1 or CHO cells	B	5.06	pKi	8647	nM	Ki	J Med Chem (2002) 45: 5353-5357 [PMID:12431062]
κ receptor/Kappa opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL237] [GtoPdb: 318] [UniProtKB: P41145]
ChEMBL	Inhibition of [3H]naltrindole (0.55 nM) binding from human Opioid receptor kappa 1	B	5.98	pKi	1057.5	nM	Ki	J Med Chem (2000) 43: 4667-4677 [PMID:11101358]
ChEMBL	Binding affinity for opioid receptor type, human Opioid receptor kappa 1 expressed in membrane homogenates of COS-1 or CHO cells	B	5.98	pKi	1057	nM	Ki	J Med Chem (2002) 45: 5353-5357 [PMID:12431062]
ChEMBL	Displacement of [3H]-naltrindole from human kappa opioid receptor expressed in human HEK293 cells after 2 hrs by scintillation counting	B	5.12	pIC50	7512	nM	IC50	Eur J Med Chem (2011) 46: 1207-1221 [PMID:21330016]
μ receptor/Mu opioid receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL233] [GtoPdb: 319] [UniProtKB: P35372]
ChEMBL	Inhibition of [3H]diprenorphine (0.33 nM) binding from human Opioid receptor mu 1 expressed in CHO-K1 cells.	B	6.99	pKi	102.9	nM	Ki	J Med Chem (2000) 43: 4667-4677 [PMID:11101358]
ChEMBL	Binding affinity for opioid receptor type, human Opioid receptor mu 1 expressed in membrane homogenates of COS-1 or CHO cells	B	6.99	pKi	102	nM	Ki	J Med Chem (2002) 45: 5353-5357 [PMID:12431062]
ChEMBL	Displacement of [3H]-naltrindole from human mu opioid receptor expressed in CHO cells after 2 hrs by scintillation counting	B	5.82	pIC50	1507	nM	IC50	Eur J Med Chem (2011) 46: 1207-1221 [PMID:21330016]
NOP receptor/Nociceptin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2014] [GtoPdb: 320] [UniProtKB: P41146]
ChEMBL	Binding affinity for opioid receptor like type, human Opioid receptor like 1 expressed in membrane homogenates of COS-1 or CHO cells	B	8.09	pKi	8.2	nM	Ki	J Med Chem (2002) 45: 5353-5357 [PMID:12431062]
ChEMBL	Ability to displace [3H]nociceptin ( 0.5 nM ) binding from Opioid receptor like 1 expressed in HeLa cells.	B	8.09	pKi	8.2	nM	Ki	J Med Chem (2000) 43: 4667-4677 [PMID:11101358]
GtoPdb	-	-	8.1	pKi	-	-	-	J Med Chem (2000) 43: 4667-77 [PMID:11101358]
ChEMBL	Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting	B	7.52	pIC50	30	nM	IC50	Eur J Med Chem (2011) 46: 1207-1221 [PMID:21330016]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]