orexin-A [Ligand Id: 1697] activity data from GtoPdb

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  • OX1 receptor in Human [GtoPdb: 321] [UniProtKB: O43613]
  • This target only has 0 pki data point
1 _lig_chart_1 OX1 receptor Human
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  • OX2 receptor in Human [GtoPdb: 322] [UniProtKB: O43614]
  • This target only has 0 pki data point
2 _lig_chart_2 OX2 receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
OX1 receptor in Human [GtoPdb: 321] [UniProtKB: O43613]
GtoPdb - - 10.2 pEC50 - - - J. Pharmacol. Exp. Ther. (2003) 305: 507-14 [PMID:12606634];
Bioorg. Med. Chem. Lett. (2001) 11: 737-40 [PMID:11266181];
J. Neurophysiol. (2003) 90: 693-702 [PMID:12702704];
Neurosci. Lett. (2001) 305: 177-80 [PMID:11403934];
FEBS Lett. (2002) 526: 11-4 [PMID:12208495];
Br. J. Pharmacol. (2007) 150: 97-104 [PMID:17115071];
Cell. Mol. Life Sci. (2008) 65: 1948-56 [PMID:18488139];
Psychopharmacology (Berl.) (2001) 153: 210-8 [PMID:11205421];
Br. J. Pharmacol. (2012) 165: 1109-23 [PMID:21718304];
Cell. Signal. (2016) 28: 51-60 [PMID:26582739];
Br. J. Pharmacol. (2004) 141: 340-6 [PMID:14691055];
Biochem. Biophys. Res. Commun. (2001) 280: 976-81 [PMID:11162621];
Cell (1998) 92: 573-85 [PMID:9491897];
Br. J. Pharmacol. (1999) 128: 1-3 [PMID:10498827];
Am. J. Physiol. Gastrointest. Liver Physiol. (2004) 287: G1182-7 [PMID:15271651];
Br. J. Pharmacol. (2010) 159: 212-21 [PMID:20002100];
Mol. Pharmacol. (2012) 82: 156-67 [PMID:22550093]
OX2 receptor in Human [GtoPdb: 322] [UniProtKB: O43614]
GtoPdb - - 10 pEC50 - - - J. Pharmacol. Exp. Ther. (2003) 305: 507-14 [PMID:12606634];
J. Neurophysiol. (2003) 90: 693-702 [PMID:12702704];
FEBS Lett. (2002) 526: 11-4 [PMID:12208495];
Biochem. Biophys. Res. Commun. (2016) 476: 379-85 [PMID:27237973];
Cell. Signal. (2016) 28: 51-60 [PMID:26582739];
Biochem. Biophys. Res. Commun. (2001) 280: 976-81 [PMID:11162621];
Cell (1998) 92: 573-85 [PMID:9491897];
Br. J. Pharmacol. (1999) 128: 1-3 [PMID:10498827];
Cell. Signal. (2008) 20: 1651-61 [PMID:18599270];
J Pharmacol Sci (2003) 92: 259-266 [PMID:12890892]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.