RP-52770 [Ligand Id: 1839] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL64716 (RP-52770)
  • Platelet activating factor receptor in Guinea pig [ChEMBL: CHEMBL5136] [UniProtKB: P21556]
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  • PAF receptor in Human [GtoPdb: 334] [UniProtKB: P25105]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Platelet activating factor receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5136] [UniProtKB: P21556]
ChEMBL Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand F 6.56 pKi 273.8 nM Ki J. Med. Chem. (1994) 37: 2011-2032 [PMID:8027984]
PAF receptor in Human [GtoPdb: 334] [UniProtKB: P25105]
GtoPdb - - 8.2 pKi - - - J Pharmacol Exp Ther (1988) 244: 709-15 [PMID:2831350]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]