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ChEMBL ligand: CHEMBL64716 (RP-52770) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Platelet activating factor receptor in Guinea pig (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5136] [UniProtKB: P21556] | ||||||||
ChEMBL | Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligand | F | 6.56 | pKi | 273.8 | nM | Ki | J. Med. Chem. (1994) 37: 2011-2032 [PMID:8027984] |
PAF receptor in Human [GtoPdb: 334] [UniProtKB: P25105] | ||||||||
GtoPdb | - | - | 8.2 | pKi | - | - | - | J Pharmacol Exp Ther (1988) 244: 709-15 [PMID:2831350] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]