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ChEMBL ligand: CHEMBL1139 (ACT-385781A, Epoprostenol, Flolan, Pgi2, PG-I2, Pgx, Prostacyclin, Prostaglandin i2, Prostaglandin x, U-53217, U-53,217) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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EP1 receptor in Human [GtoPdb: 340] [UniProtKB: P34995] | ||||||||
GtoPdb | - | - | 4.8 | pKi | - | - | - | J Pharm Pharmacol (2002) 54: 539-47 [PMID:11999132] |
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408] | ||||||||
GtoPdb | - | - | 5.1 | pKi | - | - | - | Br J Pharmacol (2000) 130: 1919-1926 [PMID:10952683] |
IP receptor in Human [GtoPdb: 345] [UniProtKB: P43119] | ||||||||
GtoPdb | - | - | 7.8 | pKi | 15.85 | nM | Ki | J Clin Invest (1979) 63: 215-20 [PMID:372237] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]