misoprostol (methyl ester) [Ligand Id: 1936] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL606 (Cytotec, SC-29333, Mysodelle, Misoprostol, Topogyne)
  • EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
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  • EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
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  • EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
GtoPdb - - 5 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
GtoPdb - - 6.5 pKi 319 nM Ki Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
GtoPdb - - 5.3 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]