misoprostol (methyl ester) [Ligand Id: 1936] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL606 (Cytotec, Misoprostol, Mysodelle, SC-29333, Topogyne)
  • EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
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  • EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
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  • EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
EP2 receptor in Human [GtoPdb: 341] [UniProtKB: P43116]
GtoPdb - - 5 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP3 receptor in Human [GtoPdb: 342] [UniProtKB: P43115]
GtoPdb - - 6.5 pKi 319 nM Ki Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]
EP4 receptor in Human [GtoPdb: 343] [UniProtKB: P35408]
GtoPdb - - 5.3 pKi - - - Biochim Biophys Acta (2000) 1483: 285-93 [PMID:10634944]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]