LY344864 [Ligand Id: 21] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL3186179
  • 5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908]
  • This target only has 1 pki data point
  • 6.3
1 CHEMBL3186179_lig_chart_1 5-HT1A receptor Human
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  • 5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222]
  • This target only has 1 pki data point
  • 6.3
2 CHEMBL3186179_lig_chart_2 5-HT1B receptor Human
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  • 5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221]
  • This target only has 1 pki data point
  • 6.2
3 CHEMBL3186179_lig_chart_3 5-HT1D receptor Human
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  • 5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566]
  • This target only has 1 pki data point
  • 5.8
4 CHEMBL3186179_lig_chart_4 5-ht1e receptor Human
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  • 5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939]
  • This target only has 1 pki data point
  • 8.2
5 CHEMBL3186179_lig_chart_5 5-HT1F receptor Human
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  • 5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223]
  • This target only has 1 pki data point
  • 5.4
6 CHEMBL3186179_lig_chart_6 5-HT2A receptor Human
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  • 5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595]
  • This target only has 1 pki data point
  • 5.8
7 CHEMBL3186179_lig_chart_7 5-HT2B receptor Human
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  • 5-HT2C receptor in Human [GtoPdb: 8] [UniProtKB: P28335]
  • This target only has 1 pki data point
  • 5.5
8 CHEMBL3186179_lig_chart_8 5-HT2C receptor Human
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  • 5-HT7 receptor in Human [GtoPdb: 12] [UniProtKB: P34969]
  • This target only has 1 pki data point
  • 5.3
9 CHEMBL3186179_lig_chart_9 5-HT7 receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908]
GtoPdb - - 6.3 pKi - - - Life Sci (1997) 61: 2117-26 [PMID:9395253]
5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222]
GtoPdb - - 6.3 pKi - - - Life Sci (1997) 61: 2117-26 [PMID:9395253]
5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221]
GtoPdb - - 6.2 pKi - - - Life Sci (1997) 61: 2117-26 [PMID:9395253]
5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566]
GtoPdb - - 5.8 pKi - - - Life Sci (1997) 61: 2117-26 [PMID:9395253]
5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939]
GtoPdb - - 8.2 pKi 6.31 nM Ki Life Sci (1997) 61: 2117-26 [PMID:9395253]
5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223]
GtoPdb - - 5.4 pKi - - - Life Sci (1997) 61: 2117-26 [PMID:9395253]
5-HT2B receptor in Human [GtoPdb: 7] [UniProtKB: P41595]
GtoPdb - - 5.8 pKi - - - Life Sci (1997) 61: 2117-26 [PMID:9395253]
5-HT2C receptor in Human [GtoPdb: 8] [UniProtKB: P28335]
GtoPdb - - 5.5 pKi - - - Life Sci (1997) 61: 2117-26 [PMID:9395253]
5-HT7 receptor in Human [GtoPdb: 12] [UniProtKB: P34969]
GtoPdb - - 5.3 pKi - - - Life Sci (1997) 61: 2117-26 [PMID:9395253]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]