FK-888 [Ligand Id: 2114] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1416993
  • NK1 receptor in Human [GtoPdb: 360] [UniProtKB: P25103]
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  • NK2 receptor in Human [GtoPdb: 361] [UniProtKB: P21452]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
NK1 receptor in Human [GtoPdb: 360] [UniProtKB: P25103]
GtoPdb - - 9.1 pKi 0.8 nM Ki Am J Respir Crit Care Med (1996) 153: 936-41 [PMID:8630576]
NK2 receptor in Human [GtoPdb: 361] [UniProtKB: P21452]
GtoPdb - - 6.1 pKi - - - Pharmacology (2002) 65: 96-102 [PMID:11937780]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]