[3H]AVP (human, mouse, rat) [Ligand Id: 2175] activity data from GtoPdb

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  • V1A receptor in Human [GtoPdb: 366] [UniProtKB: P37288]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 V1A receptor Human
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  • V1B receptor in Human [GtoPdb: 367] [UniProtKB: P47901]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 V1B receptor Human
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  • V2 receptor in Human [GtoPdb: 368] [UniProtKB: P30518]
  • V2 receptor in Rat [GtoPdb: 368] [UniProtKB: Q00788]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 V2 receptor HumanRat
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  • OT receptor in Human [GtoPdb: 369] [UniProtKB: P30559]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 OT receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
V1A receptor in Human [GtoPdb: 366] [UniProtKB: P37288]
GtoPdb - - 10.2 pKd 0.06 nM Kd J Biol Chem (1994) 269: 3304-10 [PMID:8106369];
Br J Pharmacol (1998) 125: 1463-70 [PMID:9884074];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 63-9 [PMID:9459574];
EMBO J (1995) 14: 2176-82 [PMID:7774575];
J Biol Chem (2001) 276: 26931-41 [PMID:11337500]
V1B receptor in Human [GtoPdb: 367] [UniProtKB: P47901]
GtoPdb - - 9.6 pKd 0.25 nM Kd Br J Pharmacol (1998) 125: 1463-70 [PMID:9884074];
Endocrinology (1997) 138: 4109-22 [PMID:9322919];
Endocrinology (2002) 143: 4655-64 [PMID:12446593];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 63-9 [PMID:9459574];
Biochem Pharmacol (1997) 53: 1711-1717 [PMID:9264324]
V2 receptor in Human [GtoPdb: 368] [UniProtKB: P30518]
GtoPdb - - 9.4 pKd 0.4 nM Kd Br J Pharmacol (1998) 125: 1463-70 [PMID:9884074];
Br J Pharmacol (2000) 129: 1700-6 [PMID:10780976];
Naunyn Schmiedebergs Arch Pharmacol (1998) 357: 63-9 [PMID:9459574];
J Pharmacol Exp Ther (1998) 287: 860-7 [PMID:9864265];
J Biol Chem (1998) 273: 29462-8 [PMID:9792651]
V2 receptor in Rat [GtoPdb: 368] [UniProtKB: Q00788]
GtoPdb - - 8.8 pKd - - - J Biol Chem (1998) 273: 29462-8 [PMID:9792651]
OT receptor in Human [GtoPdb: 369] [UniProtKB: P30559]
GtoPdb - - 8.9 pKd - - - EMBO J (1995) 14: 2176-82 [PMID:7774575];
J Biol Chem (2001) 276: 26931-41 [PMID:11337500]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.