BAY 55-9837 [Ligand Id: 2269] activity data from GtoPdb

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  • PAC1 receptor in Human [GtoPdb: 370] [UniProtKB: P41586]
  • This target only has 0 pki data point
1 _lig_chart_1 PAC1 receptor Human
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  • VPAC1 receptor in Human [GtoPdb: 371] [UniProtKB: P32241]
  • This target only has 0 pki data point
2 _lig_chart_2 VPAC1 receptor Human
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  • VPAC2 receptor in Human [GtoPdb: 372] [UniProtKB: P41587]
  • This target only has 0 pki data point
3 _lig_chart_3 VPAC2 receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
PAC1 receptor in Human [GtoPdb: 370] [UniProtKB: P41586]
GtoPdb inhibition of [125I]-PACAP-27 binding to membranes from CHO cells stably expressing the recombinant receptor - 5 pIC50 >10000 nM IC50 Diabetes (2002) 51: 1453-60 [PMID:11978642]
VPAC1 receptor in Human [GtoPdb: 371] [UniProtKB: P32241]
GtoPdb inhibition of [125I]-PACAP-27 binding to membranes from CHO cells stably expressing the recombinant receptor - 5.1 pIC50 8700 nM IC50 Diabetes (2002) 51: 1453-60 [PMID:11978642]
GtoPdb cyclic AMP formation in CHO cells stably expressing recombinant receptor - 7 pEC50 100 nM EC50 Diabetes (2002) 51: 1453-60 [PMID:11978642]
VPAC2 receptor in Human [GtoPdb: 372] [UniProtKB: P41587]
GtoPdb inhibition of [125I]-PACAP-27 binding to membranes from CHO cells stably expressing the recombinant receptor - 7.2 pIC50 60 nM IC50 Diabetes (2002) 51: 1453-60 [PMID:11978642]
GtoPdb cyclic AMP formation in CHO cells stably expressing recombinant receptor - 9.4 pEC50 0.4 nM EC50 Diabetes (2002) 51: 1453-60 [PMID:11978642]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.