dequalinium [Ligand Id: 2313] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL333826 (Dequalinium)
  • KCa2.1 in Human [GtoPdb: 381] [UniProtKB: Q92952]
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  • KCa2.2 in Rat [GtoPdb: 382] [UniProtKB: P70604]
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  • KCa2.3 in Human [GtoPdb: 383] [UniProtKB: Q9UGI6]
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  • CNGA1 in Human [GtoPdb: 394] [UniProtKB: P29973]
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  • CNGA2 in Human [GtoPdb: 395] [UniProtKB: Q16280]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
KCa2.1 in Human [GtoPdb: 381] [UniProtKB: Q92952]
GtoPdb - - 6.4 pIC50 400 nM IC50 Br. J. Pharmacol. (2000) 129: 627-30 [PMID:10683185];
Br. J. Pharmacol. (2000) 129: 991-9 [PMID:10696100]
KCa2.2 in Rat [GtoPdb: 382] [UniProtKB: P70604]
GtoPdb - - 6.8 pIC50 - - - Br. J. Pharmacol. (2000) 129: 991-9 [PMID:10696100];
Eur. J. Pharmacol. (2000) 401: 1-7 [PMID:10915830]
KCa2.3 in Human [GtoPdb: 383] [UniProtKB: Q9UGI6]
GtoPdb - - 4.5 pIC50 - - - Neuropharmacology (2001) 40: 772-83 [PMID:11369031]
CNGA1 in Human [GtoPdb: 394] [UniProtKB: P29973]
GtoPdb - - 6.7 pIC50 - - - J. Gen. Physiol. (2003) 121: 37-47 [PMID:12508052]
CNGA2 in Human [GtoPdb: 395] [UniProtKB: Q16280]
GtoPdb - - 5.6 pIC50 - - - J. Gen. Physiol. (2004) 123: 295-304 [PMID:14981138]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]