charybdotoxin [Ligand Id: 2328] activity data from GtoPdb

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  • KCa3.1 in Human [GtoPdb: 384] [UniProtKB: O15554]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 KCa3.1 Human
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  • Kv1.2 in Rat [GtoPdb: 539] [UniProtKB: P63142]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 Kv1.2 Rat
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  • Kv1.3 in Human [GtoPdb: 540] [UniProtKB: P22001]
  • Kv1.3 in Rat [GtoPdb: 540] [UniProtKB: P15384]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 Kv1.3 HumanRat
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  • Kv1.6 in Human [GtoPdb: 543] [UniProtKB: P17658]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 Kv1.6 Human
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  • Kv1.8 in Human [GtoPdb: 545] [UniProtKB: Q16322]
  • This target only has 0 pki data point
  • 0
5 _lig_chart_5 Kv1.8 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
KCa3.1 in Human [GtoPdb: 384] [UniProtKB: O15554]
GtoPdb - - 8.5 pKd - - - J Biol Chem (2000) 275: 37137-49 [PMID:10961988]
GtoPdb - - 8.7 pIC50 2 nM IC50 Proc Natl Acad Sci USA (1997) 94: 11013-8 [PMID:9380751];
Am J Physiol (1998) 275: C848-56 [PMID:9730970]
Kv1.2 in Rat [GtoPdb: 539] [UniProtKB: P63142]
GtoPdb - - 7.9 pKd - - - Mol Pharmacol (1994) 45: 1227-34 [PMID:7517498]
Kv1.3 in Human [GtoPdb: 540] [UniProtKB: P22001]
GtoPdb - - 9.7 pKd - - - J Biol Chem (2000) 275: 37137-49 [PMID:10961988];
J Biol Chem (1992) 267: 8650-7 [PMID:1373731];
J Gen Physiol (1989) 93: 1061-74 [PMID:2475579]
Kv1.3 in Rat [GtoPdb: 540] [UniProtKB: P15384]
GtoPdb - - 8.6 pKd - - - Mol Pharmacol (1994) 45: 1227-34 [PMID:7517498]
Kv1.6 in Human [GtoPdb: 543] [UniProtKB: P17658]
GtoPdb - - 9 pIC50 - - - EMBO J (1990) 9: 1749-56 [PMID:2347305]
Kv1.8 in Human [GtoPdb: 545] [UniProtKB: Q16322]
GtoPdb - - 7 pIC50 - - - Am J Physiol Renal Physiol (2000) 278: F1013-21 [PMID:10836990]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.