Ba2+ [Ligand Id: 2344] activity data from GtoPdb

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  • KNa1.2 in Human [GtoPdb: 386] [UniProtKB: Q6UVM3]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 KNa1.2 Human
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  • Kir1.1 in Rat [GtoPdb: 429] [UniProtKB: P35560]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 Kir1.1 Rat
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  • Kir2.1 in Mouse [GtoPdb: 430] [UniProtKB: P35561]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 Kir2.1 Mouse
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  • Kir2.2 in Rat [GtoPdb: 431] [UniProtKB: P52188]
  • This target only has 1 pki data point
  • 5.2
4 _lig_chart_4 Kir2.2 Rat
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  • Kir2.3 in Human [GtoPdb: 432] [UniProtKB: P48050]
  • Kir2.3 in Mouse [GtoPdb: 432] [UniProtKB: P52189]
  • This target only has 0 pki data point
  • 0
5 _lig_chart_5 Kir2.3 HumanMouse
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  • Kir2.4 in Human [GtoPdb: 433] [UniProtKB: Q9UNX9]
  • Kir2.4 in Rat [GtoPdb: 433] [UniProtKB: O70596]
  • This target only has 1 pki data point
  • 4.18
6 _lig_chart_6 Kir2.4 HumanRat
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  • Kir3.1 in Rat [GtoPdb: 434] [UniProtKB: P63251]
  • This target only has 0 pki data point
  • 0
7 _lig_chart_7 Kir3.1 Rat
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  • Kir3.4 in Rat [GtoPdb: 437] [UniProtKB: P48548]
  • This target only has 0 pki data point
  • 0
8 _lig_chart_8 Kir3.4 Rat
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  • Kir7.1 in Human [GtoPdb: 443] [UniProtKB: O60928]
  • This target only has 1 pki data point
  • 3.2
9 _lig_chart_9 Kir7.1 Human
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  • K2P3.1 in Human [GtoPdb: 515] [UniProtKB: O14649]
  • This target only has 0 pki data point
  • 0
10 _lig_chart_10 K2P3.1 Human
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  • Kv1.8 in Human [GtoPdb: 545] [UniProtKB: Q16322]
  • This target only has 0 pki data point
  • 0
11 _lig_chart_11 Kv1.8 Human
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  • Kv2.1 in Rat [GtoPdb: 546] [UniProtKB: P15387]
  • This target only has 0 pki data point
  • 0
12 _lig_chart_12 Kv2.1 Rat
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  • Kv12.1 in Human [GtoPdb: 575] [UniProtKB: Q96L42]
  • This target only has 0 pki data point
  • 0
13 _lig_chart_13 Kv12.1 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
KNa1.2 in Human [GtoPdb: 386] [UniProtKB: Q6UVM3]
GtoPdb - - 3 pIC50 - - - J Neurosci (2003) 23: 11681-91 [PMID:14684870]
Kir1.1 in Rat [GtoPdb: 429] [UniProtKB: P35560]
GtoPdb - - 4.2 pIC50 - - - Nature (1993) 362: 31-8 [PMID:7680431];
Am J Physiol (1996) 271: C1949-56 [PMID:8997197]
Kir2.1 in Mouse [GtoPdb: 430] [UniProtKB: P35561]
GtoPdb - - 5.6 pKd - - - J Physiol (Lond.) (2001) 534: 381-93 [PMID:11454958]
Kir2.2 in Rat [GtoPdb: 431] [UniProtKB: P52188]
GtoPdb - - 5.2 pKi - - - J Neurosci (1998) 18: 4096-105 [PMID:9592090]
Kir2.3 in Human [GtoPdb: 432] [UniProtKB: P48050]
GtoPdb - - 4.99 pIC50 - - - Proc Natl Acad Sci USA (2002) 99: 7774-9 [PMID:12032359];
J Biol Chem (1994) 269: 20468-74 [PMID:8051145];
FEBS Lett (1994) 348: 239-43 [PMID:8034048]
Kir2.3 in Mouse [GtoPdb: 432] [UniProtKB: P52189]
GtoPdb - - 5.19 pIC50 - - - FEBS Lett (1994) 346: 251-6 [PMID:8013643];
FEBS Lett (1994) 353: 37-42 [PMID:7926018]
Kir2.4 in Human [GtoPdb: 433] [UniProtKB: Q9UNX9]
GtoPdb - - 3.32 pKd - - - Am J Physiol, Cell Physiol (2000) 279: C771-84 [PMID:10942728]
Kir2.4 in Rat [GtoPdb: 433] [UniProtKB: O70596]
GtoPdb - - 4.18 pKi - - - J Neurosci (1998) 18: 4096-105 [PMID:9592090];
J Membr Biol (2006) 213: 19-29 [PMID:17347781]
Kir3.1 in Rat [GtoPdb: 434] [UniProtKB: P63251]
GtoPdb - - 4.7 pIC50 - - - Proc Natl Acad Sci USA (1993) 90: 10235-9 [PMID:8234283]
Kir3.4 in Rat [GtoPdb: 437] [UniProtKB: P48548]
GtoPdb - - 3.3 pEC50 - - - Nature (1995) 374: 135-41 [PMID:7877685]
Kir7.1 in Human [GtoPdb: 443] [UniProtKB: O60928]
GtoPdb - - 3.2 pKi - - - Neuron (1998) 20: 995-1005 [PMID:9620703];
J Neurosci (1998) 18: 8625-36 [PMID:9786970];
FEBS Lett (1998) 434: 171-6 [PMID:9738472];
J Physiol (Lond.) (2001) 531: 27-36 [PMID:11179389]
K2P3.1 in Human [GtoPdb: 515] [UniProtKB: O14649]
GtoPdb - - 0.3 pIC50 - - -
Kv1.8 in Human [GtoPdb: 545] [UniProtKB: Q16322]
GtoPdb - - 2.3 pIC50 - - - Am J Physiol Renal Physiol (2000) 278: F1013-21 [PMID:10836990]
Kv2.1 in Rat [GtoPdb: 546] [UniProtKB: P15387]
GtoPdb - - 1.5 pKd - - - Mol Pharmacol (1993) 44: 180-90 [PMID:8341271]
GtoPdb - - 4.9 pKd - - - Mol Pharmacol (1993) 44: 180-90 [PMID:8341271]
Kv12.1 in Human [GtoPdb: 575] [UniProtKB: Q96L42]
GtoPdb - - 3.7 pIC50 - - - Am J Physiol, Cell Physiol (2003) 285: C1356-66 [PMID:12890647]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.