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ChEMBL ligand: CHEMBL148333 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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cAMP-dependent protein kinase alpha-catalytic subunit in Rabbit (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4885] [UniProtKB: Q95J97] | ||||||||
ChEMBL | Inhibitory constant against cAPK (PKA) | B | 5.92 | pKi | 1200 | nM | Ki | J Biol Chem (1996) 271: 26157-26164 [PMID:8824261] |
Myosin light chain kinase, smooth muscle in Chicken (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3062] [UniProtKB: P11799] | ||||||||
ChEMBL | Inhibitory constant against MLCK | B | 4.17 | pKi | 68000 | nM | Ki | J Biol Chem (1996) 271: 26157-26164 [PMID:8824261] |
Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
ChEMBL | Antimalarial activity against drug-resistant Plasmodium falciparum D6 | F | 4.13 | pIC50 | >74000 | nM | IC50 | Bioorg Med Chem Lett (2007) 17: 4961-4966 [PMID:17588749] |
ChEMBL | Antimalarial activity against drug-resistant Plasmodium falciparum W2 | F | 4.43 | pIC50 | >37000 | nM | IC50 | Bioorg Med Chem Lett (2007) 17: 4961-4966 [PMID:17588749] |
Protein kinase Pfmrk in Plasmodium falciparum (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4090] [UniProtKB: P90584] | ||||||||
ChEMBL | Inhibition of Plasmodium falciparum Pfmrk | B | 4.15 | pIC50 | 70000 | nM | IC50 | Bioorg Med Chem Lett (2007) 17: 4961-4966 [PMID:17588749] |
CNGA1 in Rat [GtoPdb: 394] [UniProtKB: Q62927] | ||||||||
GtoPdb | - | - | 3.5 | pIC50 | - | - | - | Neurosci Lett (1997) 233: 37-40 [PMID:9324234] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]