ruthenium red [Ligand Id: 2432] activity data from GtoPdb

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  • CatSper1 in Mouse [GtoPdb: 388] [UniProtKB: Q91ZR5]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 CatSper1 Mouse
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  • CatSper2 in Mouse [GtoPdb: 389] [UniProtKB: A2ARP9]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 CatSper2 Mouse
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  • CatSper3 in Mouse [GtoPdb: 390] [UniProtKB: Q80W99]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 CatSper3 Mouse
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  • CatSper4 in Mouse [GtoPdb: 391] [UniProtKB: Q8BVN3]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 CatSper4 Mouse
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  • TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
  • This target only has 0 pki data point
  • 0
5 _lig_chart_5 TRPA1 Mouse
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  • TRPM6 in Human [GtoPdb: 498] [UniProtKB: Q9BX84]
  • This target only has 0 pki data point
  • 0
6 _lig_chart_6 TRPM6 Human
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  • TRPV1 in Human [GtoPdb: 507] [UniProtKB: Q8NER1]
  • TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433]
  • This target only has 0 pki data point
  • 0
7 _lig_chart_7 TRPV1 HumanRat
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  • TRPV2 in Human [GtoPdb: 508] [UniProtKB: Q9Y5S1]
  • TRPV2 in Mouse [GtoPdb: 508] [UniProtKB: Q9WTR1]
  • This target only has 0 pki data point
  • 0
8 _lig_chart_8 TRPV2 HumanMouse
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  • TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424]
  • This target only has 0 pki data point
  • 0
9 _lig_chart_9 TRPV3 Mouse
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  • TRPV4 in Rat [GtoPdb: 510] [UniProtKB: Q9ERZ8]
  • This target only has 0 pki data point
  • 0
10 _lig_chart_10 TRPV4 Rat
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  • TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5]
  • TRPV5 in Rabbit [GtoPdb: 511]
  • This target only has 0 pki data point
  • 0
11 _lig_chart_11 TRPV5 HumanRabbit
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  • TRPV6 in Mouse [GtoPdb: 512] [UniProtKB: Q91WD2]
  • This target only has 0 pki data point
  • 0
12 _lig_chart_12 TRPV6 Mouse
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CatSper1 in Mouse [GtoPdb: 388] [UniProtKB: Q91ZR5]
GtoPdb Whole cell patch clamp - 5 pIC50 10000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
CatSper2 in Mouse [GtoPdb: 389] [UniProtKB: A2ARP9]
GtoPdb Whole cell patch clamp. - 5 pIC50 10000 nM IC50 Mol Hum Reprod (2011) 17: 478-99 [PMID:21642646]
CatSper3 in Mouse [GtoPdb: 390] [UniProtKB: Q80W99]
GtoPdb Whole cell patch clamp electrophysiology. - 5 pIC50 10000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
CatSper4 in Mouse [GtoPdb: 391] [UniProtKB: Q8BVN3]
GtoPdb Whole cell patch clamp electrophysiology. - 5 pIC50 10000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb - - 5.5 pIC50 3550 nM IC50 J Neurosci (2005) 25: 4052-61 [PMID:15843607]
TRPM6 in Human [GtoPdb: 498] [UniProtKB: Q9BX84]
GtoPdb - - 7 pIC50 100 nM IC50
TRPV1 in Human [GtoPdb: 507] [UniProtKB: Q8NER1]
GtoPdb - - 7 pIC50 90 nM IC50
GtoPdb - - 7 pIC50 - - - Br J Pharmacol (2001) 132: 1084-94 [PMID:11226139]
TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433]
GtoPdb - - 6.7 pIC50 - - - Br J Pharmacol (2001) 132: 1084-94 [PMID:11226139]
TRPV2 in Human [GtoPdb: 508] [UniProtKB: Q9Y5S1]
GtoPdb - - 6.2 pIC50 600 nM IC50
TRPV2 in Mouse [GtoPdb: 508] [UniProtKB: Q9WTR1]
GtoPdb - - 6.2 pIC50 - - - Nature (1999) 398: 436-41 [PMID:10201375]
TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424]
GtoPdb Patch clamp electrophysiology - 6 pIC50 - - - Science (2002) 296: 2046-9 [PMID:12016205]
TRPV4 in Rat [GtoPdb: 510] [UniProtKB: Q9ERZ8]
GtoPdb - - 6.7 pIC50 - - - J Neurosci (2002) 22: 6408-14 [PMID:12151520]
TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5]
GtoPdb - - 6.9 pIC50 121 nM IC50
TRPV5 in Rabbit [GtoPdb: 511]
GtoPdb - - 6.95 pIC50 111 nM IC50 Br J Pharmacol (2001) 134: 453-62 [PMID:11588099]
TRPV6 in Mouse [GtoPdb: 512] [UniProtKB: Q91WD2]
GtoPdb - - 5 pIC50 9000 nM IC50 J Physiol (Lond.) (2001) 537: 747-61 [PMID:11744752]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.