ruthenium red [Ligand Id: 2432] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CatSper1 in Mouse [GtoPdb: 388] [UniProtKB: Q91ZR5] | ||||||||
| GtoPdb | Whole cell patch clamp | - | 5 | pIC50 | 10000 | nM | IC50 | Nature (2006) 439: 737-40 [PMID:16467839] |
| CatSper2 in Mouse [GtoPdb: 389] [UniProtKB: A2ARP9] | ||||||||
| GtoPdb | Whole cell patch clamp. | - | 5 | pIC50 | 10000 | nM | IC50 | Mol Hum Reprod (2011) 17: 478-99 [PMID:21642646] |
| CatSper3 in Mouse [GtoPdb: 390] [UniProtKB: Q80W99] | ||||||||
| GtoPdb | Whole cell patch clamp electrophysiology. | - | 5 | pIC50 | 10000 | nM | IC50 | Nature (2006) 439: 737-40 [PMID:16467839] |
| CatSper4 in Mouse [GtoPdb: 391] [UniProtKB: Q8BVN3] | ||||||||
| GtoPdb | Whole cell patch clamp electrophysiology. | - | 5 | pIC50 | 10000 | nM | IC50 | Nature (2006) 439: 737-40 [PMID:16467839] |
| TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8] | ||||||||
| GtoPdb | - | - | 5.5 | pIC50 | 3550 | nM | IC50 | J Neurosci (2005) 25: 4052-61 [PMID:15843607] |
| TRPM6 in Human [GtoPdb: 498] [UniProtKB: Q9BX84] | ||||||||
| GtoPdb | - | - | 7 | pIC50 | 100 | nM | IC50 | |
| TRPV1 in Human [GtoPdb: 507] [UniProtKB: Q8NER1] | ||||||||
| GtoPdb | - | - | 7 | pIC50 | 90 | nM | IC50 | |
| GtoPdb | - | - | 7 | pIC50 | - | - | - | Br J Pharmacol (2001) 132: 1084-94 [PMID:11226139] |
| TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433] | ||||||||
| GtoPdb | - | - | 6.7 | pIC50 | - | - | - | Br J Pharmacol (2001) 132: 1084-94 [PMID:11226139] |
| TRPV2 in Human [GtoPdb: 508] [UniProtKB: Q9Y5S1] | ||||||||
| GtoPdb | - | - | 6.2 | pIC50 | 600 | nM | IC50 | |
| TRPV2 in Mouse [GtoPdb: 508] [UniProtKB: Q9WTR1] | ||||||||
| GtoPdb | - | - | 6.2 | pIC50 | - | - | - | Nature (1999) 398: 436-41 [PMID:10201375] |
| TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424] | ||||||||
| GtoPdb | Patch clamp electrophysiology | - | 6 | pIC50 | - | - | - | Science (2002) 296: 2046-9 [PMID:12016205] |
| TRPV4 in Rat [GtoPdb: 510] [UniProtKB: Q9ERZ8] | ||||||||
| GtoPdb | - | - | 6.7 | pIC50 | - | - | - | J Neurosci (2002) 22: 6408-14 [PMID:12151520] |
| TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5] | ||||||||
| GtoPdb | - | - | 6.9 | pIC50 | 121 | nM | IC50 | |
| TRPV5 in Rabbit [GtoPdb: 511] | ||||||||
| GtoPdb | - | - | 6.95 | pIC50 | 111 | nM | IC50 | Br J Pharmacol (2001) 134: 453-62 [PMID:11588099] |
| TRPV6 in Mouse [GtoPdb: 512] [UniProtKB: Q91WD2] | ||||||||
| GtoPdb | - | - | 5 | pIC50 | 9000 | nM | IC50 | J Physiol (Lond.) (2001) 537: 747-61 [PMID:11744752] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
