ruthenium red [Ligand Id: 2432] activity data from GtoPdb

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  • CatSper1 in Mouse [GtoPdb: 388] [UniProtKB: Q91ZR5]
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  • CatSper2 in Mouse [GtoPdb: 389] [UniProtKB: A2ARP9]
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  • CatSper3 in Mouse [GtoPdb: 390] [UniProtKB: Q80W99]
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  • CatSper4 in Mouse [GtoPdb: 391] [UniProtKB: Q8BVN3]
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  • TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
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  • TRPM6 in Human [GtoPdb: 498] [UniProtKB: Q9BX84]
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  • TRPV1 in Human [GtoPdb: 507] [UniProtKB: Q8NER1]
  • TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433]
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  • TRPV2 in Human [GtoPdb: 508] [UniProtKB: Q9Y5S1]
  • TRPV2 in Mouse [GtoPdb: 508] [UniProtKB: Q9WTR1]
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  • TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424]
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  • TRPV4 in Rat [GtoPdb: 510] [UniProtKB: Q9ERZ8]
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  • TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5]
  • TRPV5 in Rabbit [GtoPdb: 511]
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  • TRPV6 in Mouse [GtoPdb: 512] [UniProtKB: Q91WD2]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CatSper1 in Mouse [GtoPdb: 388] [UniProtKB: Q91ZR5]
GtoPdb Whole cell patch clamp - 5 pIC50 10000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
CatSper2 in Mouse [GtoPdb: 389] [UniProtKB: A2ARP9]
GtoPdb Whole cell patch clamp. - 5 pIC50 10000 nM IC50 Mol. Hum. Reprod. (2011) 17: 478-99 [PMID:21642646]
CatSper3 in Mouse [GtoPdb: 390] [UniProtKB: Q80W99]
GtoPdb Whole cell patch clamp electrophysiology. - 5 pIC50 10000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
CatSper4 in Mouse [GtoPdb: 391] [UniProtKB: Q8BVN3]
GtoPdb Whole cell patch clamp electrophysiology. - 5 pIC50 10000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb - - 5.5 pIC50 3550 nM IC50 J. Neurosci. (2005) 25: 4052-61 [PMID:15843607]
TRPM6 in Human [GtoPdb: 498] [UniProtKB: Q9BX84]
GtoPdb - - 7 pIC50 100 nM IC50
TRPV1 in Human [GtoPdb: 507] [UniProtKB: Q8NER1]
GtoPdb - - 7 pIC50 90 nM IC50
GtoPdb - - 7 pIC50 - - - Br. J. Pharmacol. (2001) 132: 1084-94 [PMID:11226139]
TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433]
GtoPdb - - 6.7 pIC50 - - - Br. J. Pharmacol. (2001) 132: 1084-94 [PMID:11226139]
TRPV2 in Human [GtoPdb: 508] [UniProtKB: Q9Y5S1]
GtoPdb - - 6.2 pIC50 600 nM IC50
TRPV2 in Mouse [GtoPdb: 508] [UniProtKB: Q9WTR1]
GtoPdb - - 6.2 pIC50 - - - Nature (1999) 398: 436-41 [PMID:10201375]
TRPV3 in Mouse [GtoPdb: 509] [UniProtKB: Q8K424]
GtoPdb Patch clamp electrophysiology - 6 pIC50 - - - Science (2002) 296: 2046-9 [PMID:12016205]
TRPV4 in Rat [GtoPdb: 510] [UniProtKB: Q9ERZ8]
GtoPdb - - 6.7 pIC50 - - - J. Neurosci. (2002) 22: 6408-14 [PMID:12151520]
TRPV5 in Human [GtoPdb: 511] [UniProtKB: Q9NQA5]
GtoPdb - - 6.9 pIC50 121 nM IC50
TRPV5 in Rabbit [GtoPdb: 511]
GtoPdb - - 6.95 pIC50 111 nM IC50 Br. J. Pharmacol. (2001) 134: 453-62 [PMID:11588099]
TRPV6 in Mouse [GtoPdb: 512] [UniProtKB: Q91WD2]
GtoPdb - - 5 pIC50 9000 nM IC50 J. Physiol. (Lond.) (2001) 537: 747-61 [PMID:11744752]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.