La3+ [Ligand Id: 2434] activity data from GtoPdb

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  • TRPC3 in Human [GtoPdb: 488] [UniProtKB: Q13507]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 TRPC3 Human
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  • TRPC6 in Human [GtoPdb: 491] [UniProtKB: Q9Y210]
  • TRPC6 in Mouse [GtoPdb: 491] [UniProtKB: Q61143]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 TRPC6 HumanMouse
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  • TRPM3 in Human [GtoPdb: 495] [UniProtKB: Q9HCF6]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 TRPM3 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
TRPC3 in Human [GtoPdb: 488] [UniProtKB: Q13507]
GtoPdb - - 5.4 pIC50 4000 nM IC50 J Biol Chem (2000) 275: 37423-8 [PMID:10970899]
TRPC6 in Human [GtoPdb: 491] [UniProtKB: Q9Y210]
GtoPdb - - 5.22 pIC50 ~6000 nM IC50
TRPC6 in Mouse [GtoPdb: 491] [UniProtKB: Q61143]
GtoPdb - - 5.4 pIC50 - - - Circ Res (2001) 88: 325-32 [PMID:11179201]
TRPM3 in Human [GtoPdb: 495] [UniProtKB: Q9HCF6]
GtoPdb - - 4 pIC50 - - - J Biol Chem (2003) 278: 20890-7 [PMID:12672827];
J Biol Chem (2003) 278: 21493-501 [PMID:12672799]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.