AMP-PNP [Ligand Id: 2456] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1230989
  • S-adenosylmethionine synthetase gamma form in Rat [ChEMBL: CHEMBL2838] [UniProtKB: P18298]
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  • TRPM4 in Human [GtoPdb: 496] [UniProtKB: Q8TD43]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
S-adenosylmethionine synthetase gamma form in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2838] [UniProtKB: P18298]
ChEMBL Inhibitory constant against rat kidney Methionine adenosyltransferase II B 5.26 pKi 5500 nM Ki J. Med. Chem. (1986) 29: 318-322 [PMID:3950912]
TRPM4 in Human [GtoPdb: 496] [UniProtKB: Q8TD43]
GtoPdb - - 4.7 pIC50 - - - Pflugers Arch. (2004) 448: 70-5 [PMID:14758478]

ChEMBL data shown on this page come from version 26:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]