ChEMBL ligand: CHEMBL3286869
GluN1/GluN2A/Glutamate NMDA receptor; Grin1/Grin2a in Rat [ChEMBL: CHEMBL2096680] [GtoPdb: 455, 456] [UniProtKB: P35439, Q00959] There should be some charts here, you may need to enable JavaScript!
GluA1/Glutamate receptor ionotropic, AMPA 1 in Rat [ChEMBL: CHEMBL3753] [GtoPdb: 444] [UniProtKB: P19490] There should be some charts here, you may need to enable JavaScript!
TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
GluN1/GluN2A/Glutamate NMDA receptor; Grin1/Grin2a in Rat (target type: PROTEIN COMPLEX) [ChEMBL: CHEMBL2096680] [GtoPdb: 455, 456] [UniProtKB: P35439, Q00959]
ChEMBL	Inhibition of rat recombinant GluN1/2A expressed in Xenopus oocytes assessed as inhibition of glutamate/glycine-evoked channel current at holding potential of -80 mV by two-electrode voltage clamp technique	B	7.92	pIC50	12	nM	IC50	J. Med. Chem. (2014) 57: 4940-4949 [PMID:24824658]
GluA1/Glutamate receptor ionotropic, AMPA 1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3753] [GtoPdb: 444] [UniProtKB: P19490]
ChEMBL	Inhibition of rat recombinant GluA1 expressed in Xenopus oocytes assessed as inhibition of glutamate-induced channel current at holding potential of -80 mV by two-electrode voltage clamp technique	B	7.96	pIC50	11	nM	IC50	J. Med. Chem. (2014) 57: 4940-4949 [PMID:24824658]
TRPV1 in Rat [GtoPdb: 507] [UniProtKB: O35433]
GtoPdb	-	-	6.5	pKi	-	-	-	Biochemistry (2005) 44: 15544-9 [PMID:16300403]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]