Pb2+ [Ligand Id: 2525] activity data from GtoPdb

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  • Cav1.2 in Human [GtoPdb: 529] [UniProtKB: Q13936]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 Cav1.2 Human
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  • Cav2.2 in Human [GtoPdb: 533] [UniProtKB: Q00975]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 Cav2.2 Human
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  • Cav2.3 in Human [GtoPdb: 534] [UniProtKB: Q15878]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 Cav2.3 Human
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  • ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 ASIC1 Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Cav1.2 in Human [GtoPdb: 529] [UniProtKB: Q13936]
GtoPdb - - 6.4 pIC50 - - - Mol Pharmacol (2002) 62: 1418-30 [PMID:12435810]
Cav2.2 in Human [GtoPdb: 533] [UniProtKB: Q00975]
GtoPdb - - 5.9 pIC50 - - - Mol Pharmacol (2002) 62: 1418-30 [PMID:12435810]
Cav2.3 in Human [GtoPdb: 534] [UniProtKB: Q15878]
GtoPdb - - 7 pIC50 - - - Mol Pharmacol (2002) 62: 1418-30 [PMID:12435810]
ASIC1 in Human [GtoPdb: 684] [UniProtKB: P78348]
GtoPdb - - 5.4 pIC50 ~4000 nM IC50 J Biol Chem (2006) 281: 2497-505 [PMID:16319075]
GtoPdb - - 5.8 pIC50 ~1500 nM IC50

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.