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ChEMBL ligand: CHEMBL1312 (Reverse triiodothyronine) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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GAT1/GABA transporter 1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4054] [GtoPdb: 929] [UniProtKB: P23978] | ||||||||
ChEMBL | Inhibition of rat GAT1 expressed in HEK293 cells assessed as inhibition of [3H]GABA uptake by liquid scintillation counting | B | 4.89 | pIC50 | 13000 | nM | IC50 | J. Med. Chem. (2015) 58: 2149-2158 [PMID:25679268] |
Thyroid hormone receptor-β in Human [GtoPdb: 589] [UniProtKB: P10828] | ||||||||
GtoPdb | - | - | 7.34 | pKd | - | - | - | Mol Endocrinol (1990) 4: 227-34 [PMID:2158622] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]