vitamin D3 [Ligand Id: 2747] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL432780
  • Dual specificity phosphatase Cdc25A in Human [ChEMBL: CHEMBL3775] [UniProtKB: P30304]
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  • Farnesoid X receptor-β in Mouse [GtoPdb: 604]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Dual specificity phosphatase Cdc25A in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3775] [UniProtKB: P30304]
ChEMBL Concentration required to inhibit human Cell division cycle 25A activity; Value ranges from 0.44 uM to 0.89 uM B 6.05 pIC50 890 nM IC50 Bioorg. Med. Chem. Lett. (2004) 14: 3291-3294 [PMID:15149692]
Farnesoid X receptor-β in Mouse [GtoPdb: 604]
GtoPdb - - 5 pEC50 - - - Mol. Cell. Biol. (2003) 23: 864-72 [PMID:12529392]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]