DY131 [Ligand Id: 2834] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL192509
  • Estrogen-related receptor-γ/Estrogen-related receptor gamma in Human [ChEMBL: CHEMBL4245] [GtoPdb: 624] [UniProtKB: P62508]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Estrogen-related receptor-γ/Estrogen-related receptor gamma in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4245] [GtoPdb: 624] [UniProtKB: P62508]
ChEMBL Inhibition of [3H]4-OHT binding to Estrogen-Related Receptor gamma B 6.18 pIC50 660 nM IC50 J. Med. Chem. (2005) 48: 3107-3109 [PMID:15857113]
GtoPdb - - 6.2 pIC50 - - - Bioorg. Med. Chem. Lett. (2005) 15: 1311-3 [PMID:15713377];
J. Med. Chem. (2005) 48: 3107-9 [PMID:15857113]
ChEMBL Estrogen-Related Receptor gamma activity in FRET assay F 6.89 pEC50 130 nM EC50 J. Med. Chem. (2005) 48: 3107-3109 [PMID:15857113]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]