AM966 [Ligand Id: 2905] activity data from GtoPdb

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  • LPA4 receptor in Human [GtoPdb: 94] [UniProtKB: Q99677]
  • This target only has 0 pki data point
  • 0
1 _lig_chart_1 LPA4 receptor Human
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  • LPA1 receptor in Human [GtoPdb: 272] [UniProtKB: Q92633]
  • LPA1 receptor in Mouse [GtoPdb: 272] [UniProtKB: P61793]
  • This target only has 0 pki data point
  • 0
2 _lig_chart_2 LPA1 receptor HumanMouse
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  • LPA2 receptor in Human [GtoPdb: 273] [UniProtKB: Q9HBW0]
  • LPA2 receptor in Mouse [GtoPdb: 273] [UniProtKB: Q9JL06]
  • This target only has 0 pki data point
  • 0
3 _lig_chart_3 LPA2 receptor HumanMouse
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  • LPA3 receptor in Human [GtoPdb: 274] [UniProtKB: Q9UBY5]
  • LPA3 receptor in Mouse [GtoPdb: 274] [UniProtKB: Q9EQ31]
  • This target only has 0 pki data point
  • 0
4 _lig_chart_4 LPA3 receptor HumanMouse
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
LPA4 receptor in Human [GtoPdb: 94] [UniProtKB: Q99677]
GtoPdb - - 5.1 pIC50 - - - Br J Pharmacol (2010) 160: 1699-713 [PMID:20649573]
LPA1 receptor in Human [GtoPdb: 272] [UniProtKB: Q92633]
GtoPdb - - 7.8 pIC50 15.8 nM IC50 J Pharmacol Exp Ther (2011) 336: 693-700 [PMID:21159750]
LPA1 receptor in Mouse [GtoPdb: 272] [UniProtKB: P61793]
GtoPdb - - 7.7 pEC50 - - - Br J Pharmacol (2010) 160: 1699-713 [PMID:20649573]
LPA2 receptor in Human [GtoPdb: 273] [UniProtKB: Q9HBW0]
GtoPdb - - 5.8 pIC50 - - - Br J Pharmacol (2010) 160: 1699-713 [PMID:20649573]
LPA2 receptor in Mouse [GtoPdb: 273] [UniProtKB: Q9JL06]
GtoPdb - - 4.6 pIC50 - - - Br J Pharmacol (2010) 160: 1699-713 [PMID:20649573]
LPA3 receptor in Human [GtoPdb: 274] [UniProtKB: Q9UBY5]
GtoPdb - - 5.7 pIC50 - - - Br J Pharmacol (2010) 160: 1699-713 [PMID:20649573]
LPA3 receptor in Mouse [GtoPdb: 274] [UniProtKB: Q9EQ31]
GtoPdb - - 6.8 pIC50 - - - Br J Pharmacol (2010) 160: 1699-713 [PMID:20649573]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.