Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
LPA4 receptor in Human [GtoPdb: 94] [UniProtKB: Q99677] | ||||||||
GtoPdb | - | - | 7.35 | pKd | - | - | - | J Biol Chem (2003) 278: 25600-6 [PMID:12724320] |
LPA4 receptor in Mouse [GtoPdb: 94] [UniProtKB: Q8BLG2] | ||||||||
GtoPdb | - | - | 7.35 | pKd | 45 | nM | Kd | J Biol Chem (2003) 278: 25600-6 [PMID:12724320] |
GPR87 in Human [GtoPdb: 122] [UniProtKB: Q9BY21] | ||||||||
GtoPdb | - | - | 7.44 | pEC50 | - | - | - |
Biochem Biophys Res Commun (2007) 363: 861-6 [PMID:17905198]; Biochem Biophys Res Commun (2008) 371: 707-12 [PMID:18466763] |
LPA5 receptor in Human [GtoPdb: 124] [UniProtKB: Q9H1C0] | ||||||||
GtoPdb | - | - | 8.19 | pKd | 6.4 | nM | Kd | J Pharmacol Exp Ther (2006) 318: 619-28 [PMID:16651401] |
GtoPdb | - | - | 7.9 | pEC50 | - | - | - |
J Biol Chem (2008) 283: 21054-64 [PMID:18499677]; Bioorg Med Chem (2010) 18: 477-95 [PMID:20056548]; J Biomol Screen (2013) 18: 599-609 [PMID:23396314] |
LPA6 receptor in Human [GtoPdb: 163] [UniProtKB: P43657] | ||||||||
GtoPdb | - | - | 6 | pEC50 | - | - | - |
J Biol Chem (2009) 284: 17731-41 [PMID:19386608]; Nat Genet (2008) 40: 329-34 [PMID:18297070] |
LPA6 receptor in Mouse [GtoPdb: 163] [UniProtKB: Q8BMC0] | ||||||||
GtoPdb | - | - | 6 | pEC50 | 1000 | nM | EC50 | J Biol Chem (2009) 284: 17731-41 [PMID:19386608] |
P2RY10 in Human [GtoPdb: 165] [UniProtKB: O00398] | ||||||||
GtoPdb | - | - | 6.9 | pEC50 | - | - | - | Biochem Biophys Res Commun (2008) 371: 707-12 [PMID:18466763] |
LPA1 receptor in Mouse [GtoPdb: 272] [UniProtKB: P61793] | ||||||||
GtoPdb | - | - | 8.3 | pEC50 | 5 | nM | EC50 |
Curr Med Chem (2008) 15: 2122-31 [PMID:18781939]; J Cell Biol (1996) 135: 1071-83 [PMID:8922387]; J Neurosci (2010) 30: 7300-9 [PMID:20505096] |
LPA2 receptor in Human [GtoPdb: 273] [UniProtKB: Q9HBW0] | ||||||||
GtoPdb | - | - | 8.16 | pEC50 | - | - | - |
Mol Pharmacol (2000) 57: 753-9 [PMID:10727522]; Bioorg Med Chem Lett (2004) 14: 3473-6 [PMID:15177455] |
LPA2 receptor in Mouse [GtoPdb: 273] [UniProtKB: Q9JL06] | ||||||||
GtoPdb | - | - | 8.17 | pEC50 | 6.8 | nM | EC50 |
Curr Med Chem (2008) 15: 2122-31 [PMID:18781939]; J Biol Chem (1998) 273: 7906-10 [PMID:9525886] |
LPA3 receptor in Human [GtoPdb: 274] [UniProtKB: Q9UBY5] | ||||||||
GtoPdb | - | - | 6.69 | pKd | - | - | - | J Biol Chem (1999) 274: 27776-85 [PMID:10488122] |
LPA3 receptor in Mouse [GtoPdb: 274] [UniProtKB: Q9EQ31] | ||||||||
GtoPdb | - | - | 6.6 | pEC50 | 253 | nM | EC50 | Curr Med Chem (2008) 15: 2122-31 [PMID:18781939] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.