LPA [Ligand Id: 2906] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| LPA4 receptor in Human [GtoPdb: 94] [UniProtKB: Q99677] | ||||||||
| GtoPdb | - | - | 7.35 | pKd | - | - | - | J Biol Chem (2003) 278: 25600-6 [PMID:12724320] |
| LPA4 receptor in Mouse [GtoPdb: 94] [UniProtKB: Q8BLG2] | ||||||||
| GtoPdb | - | - | 7.35 | pKd | 45 | nM | Kd | J Biol Chem (2003) 278: 25600-6 [PMID:12724320] |
| GPR87 in Human [GtoPdb: 122] [UniProtKB: Q9BY21] | ||||||||
| GtoPdb | - | - | 7.44 | pEC50 | - | - | - |
Biochem Biophys Res Commun (2007) 363: 861-6 [PMID:17905198]; Biochem Biophys Res Commun (2008) 371: 707-12 [PMID:18466763] |
| LPA5 receptor in Human [GtoPdb: 124] [UniProtKB: Q9H1C0] | ||||||||
| GtoPdb | - | - | 8.19 | pKd | 6.4 | nM | Kd | J Pharmacol Exp Ther (2006) 318: 619-28 [PMID:16651401] |
| GtoPdb | - | - | 7.9 | pEC50 | - | - | - |
J Biol Chem (2008) 283: 21054-64 [PMID:18499677]; Bioorg Med Chem (2010) 18: 477-95 [PMID:20056548]; J Biomol Screen (2013) 18: 599-609 [PMID:23396314] |
| LPA6 receptor in Human [GtoPdb: 163] [UniProtKB: P43657] | ||||||||
| GtoPdb | - | - | 6 | pEC50 | - | - | - |
J Biol Chem (2009) 284: 17731-41 [PMID:19386608]; Nat Genet (2008) 40: 329-34 [PMID:18297070] |
| LPA6 receptor in Mouse [GtoPdb: 163] [UniProtKB: Q8BMC0] | ||||||||
| GtoPdb | - | - | 6 | pEC50 | 1000 | nM | EC50 | J Biol Chem (2009) 284: 17731-41 [PMID:19386608] |
| P2RY10 in Human [GtoPdb: 165] [UniProtKB: O00398] | ||||||||
| GtoPdb | - | - | 6.9 | pEC50 | - | - | - | Biochem Biophys Res Commun (2008) 371: 707-12 [PMID:18466763] |
| LPA1 receptor in Mouse [GtoPdb: 272] [UniProtKB: P61793] | ||||||||
| GtoPdb | - | - | 8.3 | pEC50 | 5 | nM | EC50 |
Curr Med Chem (2008) 15: 2122-31 [PMID:18781939]; J Cell Biol (1996) 135: 1071-83 [PMID:8922387]; J Neurosci (2010) 30: 7300-9 [PMID:20505096] |
| LPA2 receptor in Human [GtoPdb: 273] [UniProtKB: Q9HBW0] | ||||||||
| GtoPdb | - | - | 8.16 | pEC50 | - | - | - |
Mol Pharmacol (2000) 57: 753-9 [PMID:10727522]; Bioorg Med Chem Lett (2004) 14: 3473-6 [PMID:15177455] |
| LPA2 receptor in Mouse [GtoPdb: 273] [UniProtKB: Q9JL06] | ||||||||
| GtoPdb | - | - | 8.17 | pEC50 | 6.8 | nM | EC50 |
Curr Med Chem (2008) 15: 2122-31 [PMID:18781939]; J Biol Chem (1998) 273: 7906-10 [PMID:9525886] |
| LPA3 receptor in Human [GtoPdb: 274] [UniProtKB: Q9UBY5] | ||||||||
| GtoPdb | - | - | 6.69 | pKd | - | - | - | J Biol Chem (1999) 274: 27776-85 [PMID:10488122] |
| LPA3 receptor in Mouse [GtoPdb: 274] [UniProtKB: Q9EQ31] | ||||||||
| GtoPdb | - | - | 6.6 | pEC50 | 253 | nM | EC50 | Curr Med Chem (2008) 15: 2122-31 [PMID:18781939] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
