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ChEMBL ligand: CHEMBL1221649 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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S1P1 receptor/Sphingosine 1-phosphate receptor Edg-1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4333] [GtoPdb: 275] [UniProtKB: P21453] | ||||||||
GtoPdb | - | - | 7.11 | pKi | 77 | nM | Ki | Nat Chem Biol (2006) 2: 434-41 [PMID:16829954] |
ChEMBL | Antagonist activity at human S1P1 receptor expressed in CHO cells assessed as inhibition of S1P-induced [35S]GTPgamma binding | F | 7.11 | pKi | 77 | nM | Ki | Nat. Chem. Biol. (2006) 2: 434-441 [PMID:16829954] |
ChEMBL | Antagonist activity at human S1P1 receptor expressed in CHO cells assessed as inhibition of SEW2871-induced [35S]GTPgamma binding | F | 7.74 | pKi | 18 | nM | Ki | Nat. Chem. Biol. (2006) 2: 434-441 [PMID:16829954] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]