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ChEMBL ligand: CHEMBL312125 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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squalene synthase /Squalene synthetase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769] | ||||||||
GtoPdb | Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assay | - | 8 | pIC50 | 10 | nM | IC50 | Bioorg Med Chem Lett (1996) 6: 2491-2494 |
ChEMBL | Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assay | B | 8 | pIC50 | 10 | nM | IC50 | Bioorg. Med. Chem. Lett. (1996) 6: 2491-2494 |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]