compound 4 [Brinkman et al., 1996] [Ligand Id: 3097] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL312125
  • squalene synthase /Squalene synthetase in Rat [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
squalene synthase /Squalene synthetase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
GtoPdb Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assay - 8 pIC50 10 nM IC50 Bioorg Med Chem Lett (1996) 6: 2491-2494
ChEMBL Compound was tested for inhibitory activity against squalene synthase using rat liver microsomal assay B 8 pIC50 10 nM IC50 Bioorg. Med. Chem. Lett. (1996) 6: 2491-2494

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]