compound 5j [PMID: 9216829] [Ligand Id: 3099] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL303461
  • squalene synthase /Squalene synthetase in Rat [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
squalene synthase /Squalene synthetase in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3815] [GtoPdb: 645] [UniProtKB: Q02769]
ChEMBL In vitro inhibitory activity against Squalene Synthase B 7.89 pIC50 13 nM IC50 J. Med. Chem. (1997) 40: 2123-2125 [PMID:9216829]
GtoPdb In vitro inhibitory activity against Squalene Synthase. Enzyme from rat liver microsomes. - 7.89 pIC50 13 nM IC50 J. Med. Chem. (1997) 40: 2123-5 [PMID:9216829]

ChEMBL data shown on this page come from version 26:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]