hexahydrosiladifenidol [Ligand Id: 310] activity data from GtoPdb

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  • M1 receptor in Human [GtoPdb: 13] [UniProtKB: P11229]
  • M1 receptor in Rat [GtoPdb: 13] [UniProtKB: P08482]
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  • M2 receptor in Human [GtoPdb: 14] [UniProtKB: P08172]
  • M2 receptor in Rat [GtoPdb: 14] [UniProtKB: P10980]
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  • M3 receptor in Human [GtoPdb: 15] [UniProtKB: P20309]
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  • M4 receptor in Human [GtoPdb: 16] [UniProtKB: P08173]
  • M4 receptor in Rat [GtoPdb: 16] [UniProtKB: P08485]
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  • M5 receptor in Human [GtoPdb: 17] [UniProtKB: P08912]
  • M5 receptor in Rat [GtoPdb: 17] [UniProtKB: P08911]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
M1 receptor in Human [GtoPdb: 13] [UniProtKB: P11229]
GtoPdb - - 7.7 pKi - - - Biochem Pharmacol (1996) 52: 643-58 [PMID:8759038]
M1 receptor in Rat [GtoPdb: 13] [UniProtKB: P08482]
GtoPdb - - 7.9 pKi - - - Life Sci (1992) 51: 955-71 [PMID:1325587];
Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]
M2 receptor in Human [GtoPdb: 14] [UniProtKB: P08172]
GtoPdb - - 6.8 pKi - - - Biochem Pharmacol (1996) 52: 643-58 [PMID:8759038];
Mol Pharmacol (1989) 35: 469-76 [PMID:2704370];
J Pharmacol Exp Ther (1998) 284: 500-7 [PMID:9454790]
M2 receptor in Rat [GtoPdb: 14] [UniProtKB: P10980]
GtoPdb - - 6.8 pKi - - - Life Sci (1992) 51: 955-71 [PMID:1325587];
J Pharmacol Exp Ther (1998) 284: 500-7 [PMID:9454790]
M3 receptor in Human [GtoPdb: 15] [UniProtKB: P20309]
GtoPdb - - 8 pKi - - - Biochem Pharmacol (1996) 52: 643-58 [PMID:8759038];
Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]
M4 receptor in Human [GtoPdb: 16] [UniProtKB: P08173]
GtoPdb - - 7.7 pKi - - - Biochem Pharmacol (1996) 52: 643-58 [PMID:8759038];
Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]
M4 receptor in Rat [GtoPdb: 16] [UniProtKB: P08485]
GtoPdb - - 7.7 pKi - - - Life Sci (1992) 51: 955-71 [PMID:1325587]
M5 receptor in Human [GtoPdb: 17] [UniProtKB: P08912]
GtoPdb - - 7.2 pKi - - - Biochem Pharmacol (1996) 52: 643-58 [PMID:8759038];
Mol Pharmacol (1989) 35: 469-76 [PMID:2704370]
M5 receptor in Rat [GtoPdb: 17] [UniProtKB: P08911]
GtoPdb - - 7.4 pKi - - - Life Sci (1992) 51: 955-71 [PMID:1325587]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.