derenofylline [Ligand Id: 3281] activity data from GtoPdb

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  • A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
  • A1 receptor in Rat [GtoPdb: 18] [UniProtKB: P25099]
1 _lig_chart_1 A1 receptor HumanRat
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  • A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
  • This target only has 1 pki data point
2 _lig_chart_2 A2A receptor Human
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  • A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
  • A2B receptor in Rat [GtoPdb: 20] [UniProtKB: P29276]
3 _lig_chart_3 A2B receptor HumanRat
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  • A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
  • This target only has 1 pki data point
4 _lig_chart_4 A3 receptor Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A1 receptor in Human [GtoPdb: 18] [UniProtKB: P30542]
GtoPdb - - 9 pKi 1 nM Ki Br. J. Pharmacol. (2007) 151: 1025-32 [PMID:17558436]
A1 receptor in Rat [GtoPdb: 18] [UniProtKB: P25099]
GtoPdb - - 8.6 pKi 2.51 nM Ki Br. J. Pharmacol. (2007) 151: 1025-32 [PMID:17558436]
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
GtoPdb - - 6.4 pKi 398 nM Ki Br. J. Pharmacol. (2007) 151: 1025-32 [PMID:17558436]
A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
GtoPdb - - 5.4 pKi 3981 nM Ki Br. J. Pharmacol. (2007) 151: 1025-32 [PMID:17558436]
A2B receptor in Rat [GtoPdb: 20] [UniProtKB: P29276]
GtoPdb - - 6.3 pKi 501 nM Ki Br. J. Pharmacol. (2007) 151: 1025-32 [PMID:17558436]
A3 receptor in Human [GtoPdb: 21] [UniProtKB: P0DMS8]
GtoPdb - - 6.7 pKi 200 nM Ki Br. J. Pharmacol. (2007) 151: 1025-32 [PMID:17558436]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.