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ChEMBL ligand: CHEMBL157822 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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cGMP-dependent protein kinase 1 alpha in Bovine (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3183] [UniProtKB: P00516] | ||||||||
ChEMBL | Tested for inhibition of cGMP-dependent protein kinase from bovine lung | B | 5.32 | pIC50 | 4800 | nM | IC50 | Bioorg. Med. Chem. Lett. (1995) 5: 55-60 |
myosin light chain kinase/Myosin light chain kinase, smooth muscle in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2428] [GtoPdb: 1552] [UniProtKB: Q15746] | ||||||||
ChEMBL | Tested for inhibition of Myosin light chain kinase from chicken gizzard | B | 6.92 | pIC50 | 120 | nM | IC50 | Bioorg. Med. Chem. Lett. (1995) 5: 55-60 |
M1 receptor in Human [GtoPdb: 13] [UniProtKB: P11229] | ||||||||
GtoPdb | - | - | 5.8 | pKd | - | - | - | Mol Pharmacol (2000) 58: 194-207 [PMID:10860942] |
M2 receptor in Human [GtoPdb: 14] [UniProtKB: P08172] | ||||||||
GtoPdb | - | - | 5 | pKd | - | - | - | Mol Pharmacol (2000) 58: 194-207 [PMID:10860942] |
M3 receptor in Human [GtoPdb: 15] [UniProtKB: P20309] | ||||||||
GtoPdb | - | - | 5.1 | pKd | - | - | - | Mol Pharmacol (2000) 58: 194-207 [PMID:10860942] |
M4 receptor in Human [GtoPdb: 16] [UniProtKB: P08173] | ||||||||
GtoPdb | - | - | 5.7 | pKd | - | - | - | Mol Pharmacol (2000) 58: 194-207 [PMID:10860942] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]