ACTH [Ligand Id: 3633] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1201610 (Acth, Acthar, Acthar gel, Adrenocorticotropic Hormone, Adrenocorticotropin, Adrenomone, Corticotropin, Corticotropin, repository, Cortigel, Cortrophin, H.p. acthar gel, Purified cortrophin gel, Repository corticotropin) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| MC1 receptor in Human [GtoPdb: 282] [UniProtKB: Q01726] | ||||||||
| GtoPdb | - | - | 8.6 | pKi | 2.5 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
| MC3 receptor in Human [GtoPdb: 284] [UniProtKB: P41968] | ||||||||
| GtoPdb | - | - | 7.06 | pKi | 86.9 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
| MC4 receptor in Human [GtoPdb: 285] [UniProtKB: P32245] | ||||||||
| GtoPdb | - | - | 6.16 | pKi | 693 | nM | Ki | Pharmacol Toxicol (1996) 79: 161-5 [PMID:8884876] |
| MC5 receptor in Human [GtoPdb: 286] [UniProtKB: P33032] | ||||||||
| GtoPdb | - | - | 5 | pKi | >10000 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
