ACTH [Ligand Id: 3633] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL1201610 (Acth, Acthar, Acthar gel, Adrenocorticotrophin, Adrenocorticotropic hormone, Adrenocorticotropic Hormone, Adrenocorticotropin, Adrenomone, Corticotrophin, Corticotropin, Corticotropina, Corticotropin (acth), Corticotropine, Corticotropin in gelatin matrix, Corticotropin, repository, Cortigel, Cortrophin, H.p. acthar gel, Purified cortrophin gel, Repository corticotropin) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| MC1 receptor in Human [GtoPdb: 282] [UniProtKB: Q01726] | ||||||||
| GtoPdb | - | - | 8.6 | pKi | 2.5 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
| MC3 receptor in Human [GtoPdb: 284] [UniProtKB: P41968] | ||||||||
| GtoPdb | - | - | 7.06 | pKi | 86.9 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
| MC4 receptor in Human [GtoPdb: 285] [UniProtKB: P32245] | ||||||||
| GtoPdb | - | - | 6.16 | pKi | 693 | nM | Ki | Pharmacol Toxicol (1996) 79: 161-5 [PMID:8884876] |
| MC5 receptor in Human [GtoPdb: 286] [UniProtKB: P33032] | ||||||||
| GtoPdb | - | - | 5 | pKi | >10000 | nM | Ki | Eur J Pharmacol (1995) 288: 311-317 [PMID:7774675] |
ChEMBL data shown on this page come from version 35:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
