donitriptan [Ligand Id: 39] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL1742428 (Donitriptan, F-11356)
  • 5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908]
There should be some charts here, you may need to enable JavaScript!
  • 5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222]
  • 5-HT1B receptor in Rat [GtoPdb: 2] [UniProtKB: P28564]
There should be some charts here, you may need to enable JavaScript!
  • 5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221]
  • 5-HT1D receptor in Rat [GtoPdb: 3] [UniProtKB: P28565]
There should be some charts here, you may need to enable JavaScript!
  • 5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566]
There should be some charts here, you may need to enable JavaScript!
  • 5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939]
There should be some charts here, you may need to enable JavaScript!
  • 5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223]
There should be some charts here, you may need to enable JavaScript!
  • 5-HT5A receptor in Human [GtoPdb: 10] [UniProtKB: P47898]
There should be some charts here, you may need to enable JavaScript!
  • 5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT1A receptor in Human [GtoPdb: 1] [UniProtKB: P08908]
GtoPdb - - 7.6 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222]
GtoPdb - - 9.4 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-HT1B receptor in Rat [GtoPdb: 2] [UniProtKB: P28564]
GtoPdb - - 9.7 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221]
GtoPdb - - 9.3 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-HT1D receptor in Rat [GtoPdb: 3] [UniProtKB: P28565]
GtoPdb - - 9.6 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-ht1e receptor in Human [GtoPdb: 4] [UniProtKB: P28566]
GtoPdb - - 5.9 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-HT1F receptor in Human [GtoPdb: 5] [UniProtKB: P30939]
GtoPdb - - 5.5 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-HT2A receptor in Human [GtoPdb: 6] [UniProtKB: P28223]
GtoPdb - - 6.7 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-HT5A receptor in Human [GtoPdb: 10] [UniProtKB: P47898]
GtoPdb - - 6.1 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]
5-HT6 receptor in Human [GtoPdb: 11] [UniProtKB: P50406]
GtoPdb - - 5.6 pKi - - - J. Pharmacol. Exp. Ther. (1999) 290: 83-95 [PMID:10381763]

ChEMBL data shown on this page come from version 26:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]