hexamethonium [Ligand Id: 3963] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL100622
  • nicotinic acetylcholine receptor α4 subunit in Human [GtoPdb: 465] [UniProtKB: P43681]
  • This target only has 0 pki data point
  • 0
1 CHEMBL100622_lig_chart_1 nicotinic acetylcholine receptor α4 subunit Human
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  • nicotinic acetylcholine receptor α6 subunit in Human [GtoPdb: 467] [UniProtKB: Q15825]
  • This target only has 0 pki data point
  • 0
2 CHEMBL100622_lig_chart_2 nicotinic acetylcholine receptor α6 subunit Human
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
nicotinic acetylcholine receptor α4 subunit in Human [GtoPdb: 465] [UniProtKB: P43681]
GtoPdb - - 4.04 pIC50 91000 nM IC50
GtoPdb - - 5.17 pIC50 6800 nM IC50
nicotinic acetylcholine receptor α6 subunit in Human [GtoPdb: 467] [UniProtKB: Q15825]
GtoPdb - - 4.04 pIC50 91000 nM IC50

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]