camicinal [Ligand Id: 4035] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL489095 (Camicinal, Gsk962040, GSK-962040, GSK962040, GSK-962040B, GSK962040B) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| ghrelin receptor/Ghrelin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4616] [GtoPdb: 246] [UniProtKB: Q92847] | ||||||||
| ChEMBL | Agonist activity at human Ghrelin receptor | F | 6 | pEC50 | >1000 | nM | EC50 | J Med Chem (2009) 52: 1180-1189 [PMID:19191554] |
| Kv11.1/HERG in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL240] [GtoPdb: 572] [UniProtKB: Q12809] | ||||||||
| ChEMBL | Binding affinity to human ERG | B | 4.8 | pIC50 | 15848.93 | nM | IC50 | J Med Chem (2009) 52: 1180-1189 [PMID:19191554] |
| motilin receptor/Motilin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2203] [GtoPdb: 297] [UniProtKB: O43193] | ||||||||
| ChEMBL | Agonist activity at human GPR38 expressed in COS-7 cells | F | 6.01 | pEC50 | 970 | nM | EC50 | Bioorg Med Chem Lett (2022) 59: 128554-128554 [PMID:35051575] |
| ChEMBL | Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assay | F | 7.9 | pEC50 | 12.59 | nM | EC50 | J Med Chem (2009) 52: 1180-1189 [PMID:19191554] |
| GtoPdb | - | - | 7.9 | pEC50 | - | - | - |
Neurogastroenterol Motil (2009) 21: 657-64, e30-1 [PMID:19374732]; Expert Opin Investig Drugs (2015) 24: 133-140 [PMID:25341626] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
