camicinal [Ligand Id: 4035] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL489095 (Camicinal, Gsk962040, GSK-962040, GSK962040, GSK-962040B, GSK962040B) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| ghrelin receptor/Ghrelin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4616] [GtoPdb: 246] [UniProtKB: Q92847] | ||||||||
| ChEMBL | Agonist activity at human Ghrelin receptor | F | 6 | pEC50 | >1000 | nM | EC50 | J Med Chem (2009) 52: 1180-1189 [PMID:19191554] |
| Kv11.1/HERG in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL240] [GtoPdb: 572] [UniProtKB: Q12809] | ||||||||
| ChEMBL | Binding affinity to human ERG | B | 4.8 | pIC50 | 15848.93 | nM | IC50 | J Med Chem (2009) 52: 1180-1189 [PMID:19191554] |
| motilin receptor/Motilin receptor in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2203] [GtoPdb: 297] [UniProtKB: O43193] | ||||||||
| ChEMBL | Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assay | F | 7.9 | pEC50 | 12.59 | nM | EC50 | J Med Chem (2009) 52: 1180-1189 [PMID:19191554] |
| GtoPdb | - | - | 7.9 | pEC50 | - | - | - |
Neurogastroenterol Motil (2009) 21: 657-64, e30-1 [PMID:19374732]; Expert Opin Investig Drugs (2015) 24: 133-140 [PMID:25341626] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
