picrotoxin [Ligand Id: 4051] activity data from GtoPdb

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  • 5-HT3AB in Mouse [GtoPdb: 378]
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  • 5-HT3A in Mouse [GtoPdb: 379]
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  • glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
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  • glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
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  • glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT3AB in Mouse [GtoPdb: 378]
GtoPdb - - 2.9 pIC50 - - - J Pharmacol Exp Ther (2005) 314: 320-8 [PMID:15814570];
Brain Res Mol Brain Res (2003) 119: 207-12 [PMID:14625088]
5-HT3A in Mouse [GtoPdb: 379]
GtoPdb - - 4.5 pIC50 - - - Brain Res Mol Brain Res (2003) 119: 207-12 [PMID:14625088];
Neuropharmacology (2003) 44: 431-8 [PMID:12646280]
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
GtoPdb - - 5.2 pIC50 6300 nM IC50
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
GtoPdb - - 5.6 pIC50 2300 nM IC50
glycine receptor β subunit in Human [GtoPdb: 427] [UniProtKB: P48167]
GtoPdb - - 3.7 pIC50 219000 nM IC50
GtoPdb - - 4.5 pIC50 29700 nM IC50

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.