Cu2+ [Ligand Id: 4164] activity data from GtoPdb

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  • glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
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  • glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
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  • glycine receptor α3 subunit in Human [GtoPdb: 425] [UniProtKB: O75311]
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  • TRPA1 in Human [GtoPdb: 485] [UniProtKB: O75762]
  • TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
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  • ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
glycine receptor α1 subunit in Human [GtoPdb: 423] [UniProtKB: P23415]
GtoPdb - - 5.4 pIC50 4000 nM IC50
glycine receptor α2 subunit in Human [GtoPdb: 424] [UniProtKB: P23416]
GtoPdb - - 4.8 pIC50 17000 nM IC50
glycine receptor α3 subunit in Human [GtoPdb: 425] [UniProtKB: O75311]
GtoPdb - - 5 pIC50 9000 nM IC50
TRPA1 in Human [GtoPdb: 485] [UniProtKB: O75762]
GtoPdb Sodium imaging - 5.89 pEC50 1300 nM EC50 Proc. Natl. Acad. Sci. U.S.A. (2009) 106: 8374-9 [PMID:19416844];
Mol Pain (2013) 9: 7 [PMID:23448290]
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb - - 6.22 pEC50 600 nM EC50 Proc. Natl. Acad. Sci. U.S.A. (2009) 106: 8374-9 [PMID:19416844];
Mol Pain (2013) 9: 7 [PMID:23448290]
ZAC in Human [GtoPdb: 587] [UniProtKB: Q401N2]
GtoPdb - - 5.4 pEC50 - - - Biochem. Pharmacol. (2016) 103: 109-17 [PMID:26872532]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.