kainate [Ligand Id: 4231] activity data from GtoPdb

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  • GluK1 in Human [GtoPdb: 450] [UniProtKB: P39086]
  • This target only has 1 pki data point
  • 6.75
1 _lig_chart_1 GluK1 Human
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  • GluK2 in Human [GtoPdb: 451] [UniProtKB: Q13002]
  • GluK2 in Rat [GtoPdb: 451] [UniProtKB: P42260]
  • 8.43
2 _lig_chart_2 GluK2 HumanRat
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  • GluK3 in Rat [GtoPdb: 452] [UniProtKB: P42264]
  • This target only has 1 pki data point
  • 7.48
3 _lig_chart_3 GluK3 Rat
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
GluK1 in Human [GtoPdb: 450] [UniProtKB: P39086]
GtoPdb - - 6.75 pKi 177 nM Ki Neuropharmacology (1998) 37: 1261-7 [PMID:9849663]
GluK2 in Human [GtoPdb: 451] [UniProtKB: Q13002]
GtoPdb Measured using kainic acid. - 7.49 pKi 32 nM Ki J Med Chem (1996) 39: 3617-24 [PMID:8809152];
Neuropharmacology (1998) 37: 1261-7 [PMID:9849663]
GluK2 in Rat [GtoPdb: 451] [UniProtKB: P42260]
GtoPdb Measured using kainic acid in rat forebrain homogenate. - 8.43 pKi 3.7 nM Ki J Pharmacol Exp Ther (1997) 280: 422-7 [PMID:8996224];
J Med Chem (1996) 39: 3617-24 [PMID:8809152]
GluK3 in Rat [GtoPdb: 452] [UniProtKB: P42264]
GtoPdb - - 7.48 pKi 32.8 nM Ki J Med Chem (2008) 51: 4093-103 [PMID:18578478]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.