ChEMBL ligand: CHEMBL341748
GluA4/Glutamate receptor ionotropic, AMPA 4 in Human [ChEMBL: CHEMBL3190] [GtoPdb: 447] [UniProtKB: P48058] There should be some charts here, you may need to enable JavaScript!
GluA1 in Human [GtoPdb: 444] [UniProtKB: P42261] There should be some charts here, you may need to enable JavaScript!
GluA2 in Human [GtoPdb: 445] [UniProtKB: P42262] There should be some charts here, you may need to enable JavaScript!
GluA3 in Human [GtoPdb: 446] [UniProtKB: P42263] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
GluA4/Glutamate receptor ionotropic, AMPA 4 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3190] [GtoPdb: 447] [UniProtKB: P48058]
ChEMBL	Tested for potentiation towards human iGluR4 receptor expressed in HEK293 cells	F	5.36	pEC50	4400	nM	EC50	J. Med. Chem. (2000) 43: 4354-4358 [PMID:11087558]
GtoPdb	-	-	6.7	pEC50	200	nM	EC50	Neuropharmacology (2001) 40: 976-83 [PMID:11406188]
GluA1 in Human [GtoPdb: 444] [UniProtKB: P42261]
GtoPdb	-	-	5.75	pEC50	1770	nM	EC50	Neuropharmacology (2001) 40: 976-83 [PMID:11406188]
GluA2 in Human [GtoPdb: 445] [UniProtKB: P42262]
GtoPdb	-	-	6.66	pEC50	220	nM	EC50	Neuropharmacology (2001) 40: 976-83 [PMID:11406188]
GluA3 in Human [GtoPdb: 446] [UniProtKB: P42263]
GtoPdb	-	-	5.72	pEC50	1890	nM	EC50	Neuropharmacology (2001) 40: 976-83 [PMID:11406188]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]