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ChEMBL ligand: CHEMBL211502 (Phenamil) |
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CHEMBL211502_lig_chart_2
TRPP2
Human
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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ENaC α/Amiloride-sensitive sodium channel alpha-subunit in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1791] [GtoPdb: 738] [UniProtKB: P37088] | ||||||||
ChEMBL | Inhibition of dog bronchi prototypical epithelial sodium channel by electrophysiological assay | B | 6.4 | pIC50 | 401 | nM | IC50 | J. Med. Chem. (2006) 49: 4098-4115 [PMID:16821771] |
TRPP2 in Human [GtoPdb: 505] [UniProtKB: Q9P0L9] | ||||||||
GtoPdb | - | - | 6.9 | pIC50 | 140 | nM | IC50 |
ChEMBL data shown on this page come from version 27:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]