CXCL12α [Ligand Id: 4358] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| CXCR3 in Human [GtoPdb: 70] [UniProtKB: P49682] | ||||||||
| GtoPdb | - | - | 6.4 | pKi | - | - | - | J Biol Chem (1998) 273: 18288-91 [PMID:9660793] |
| CXCR4 in Human [GtoPdb: 71] [UniProtKB: P61073] | ||||||||
| GtoPdb | - | - | 8.2 | pKd | - | - | - |
J Immunol (1998) 160: 877-83 [PMID:9551924]; J Biol Chem (1998) 273: 22279-83 [PMID:9712844] |
| GtoPdb | Measuring CXCL12-induced displacement of CXCR4-bound 125I-CXCL12 from membranes prepared from HEK293T cells expressing human CXCR4. | - | 9.3 | pIC50 | 0.5 | nM | IC50 | Eur J Med Chem (2019) 162: 631-649 [PMID:30476826] |
| ACKR3 in Human [GtoPdb: 80] [UniProtKB: P25106] | ||||||||
| GtoPdb | - | - | 7.9 | pEC50 | - | - | - |
J Biol Chem (2010) 285: 37939-43 [PMID:20956518]; J Biomol Screen (2013) 18: 599-609 [PMID:23396314] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
