[3H]hemicholinium-3 [Ligand Id: 4493] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL197027
  • Vesicular acetylcholine transporter in Human [ChEMBL: CHEMBL4767] [GtoPdb: 1013] [UniProtKB: Q16572]
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  • CHT in Human [GtoPdb: 914] [UniProtKB: Q9GZV3]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Vesicular acetylcholine transporter in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4767] [GtoPdb: 1013] [UniProtKB: Q16572]
ChEMBL Percent inhibition against Acetylcholine transporter at 1 uM B 7.92 pIC50 12 nM IC50 J. Med. Chem. (2005) 48: 6887-6896 [PMID:16250647]
CHT in Human [GtoPdb: 914] [UniProtKB: Q9GZV3]
GtoPdb - - 8.4 pKd 4 nM Kd

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]