ChEMBL ligand: CHEMBL453904 (Bromosulfalein, Bromsulphthalein, Bromthalein, Bsp sodium, Hepartest, Hepatestabrome, Hepatosulfalein, Sodium Bromsulphalein, Sodium bromsulphthalein, Sulfobromophthalein, Sulfobromophthalein sodium, Sulfobromopthalein sodium, Sulfobromphthalein sodium, Sulphobromophthalein)
Sodium/bile acid and sulphated solute cotransporter 1/Bile acid transporter in Human [ChEMBL: CHEMBL5287] [GtoPdb: 959] [UniProtKB: Q14973] There should be some charts here, you may need to enable JavaScript!
ABCC2/Canalicular multispecific organic anion transporter 1 in Rat [ChEMBL: CHEMBL2073676] [GtoPdb: 780] [UniProtKB: Q63120] There should be some charts here, you may need to enable JavaScript!
Solute carrier organic anion transporter family member 1A1 in Rat [ChEMBL: CHEMBL1781859] [UniProtKB: P46720] There should be some charts here, you may need to enable JavaScript!
Solute carrier organic anion transporter family member 1A3 in Rat [ChEMBL: CHEMBL2073707] [UniProtKB: P70502] There should be some charts here, you may need to enable JavaScript!
OATP1B1/Solute carrier organic anion transporter family member 1B1 in Human [ChEMBL: CHEMBL1697668] [GtoPdb: 1220] [UniProtKB: Q9Y6L6] There should be some charts here, you may need to enable JavaScript!
OATP2A1/Solute carrier organic anion transporter family member 2A1 in Rat [ChEMBL: CHEMBL2073680] [GtoPdb: 1223] [UniProtKB: Q00910] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Sodium/bile acid and sulphated solute cotransporter 1/Bile acid transporter in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5287] [GtoPdb: 959] [UniProtKB: Q14973]
ChEMBL	TP_TRANSPORTER: inhibition of Taurocholate uptake in NTCP-expressing HeLa cells	F	5.14	pIC50	7300	nM	IC50	J Pharmacol Exp Ther (1999) 291: 1204-1209 [PMID:10565843]
ABCC2/Canalicular multispecific organic anion transporter 1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073676] [GtoPdb: 780] [UniProtKB: Q63120]
ChEMBL	TP_TRANSPORTER: inhibition of SN-38 uptake in bile canalicular membrane vesicles from SD rat	F	5.54	pKi	2870	nM	Ki	Drug Metabol Pharmacokin (2002) 17: 23-33 [PMID:15618649]
ChEMBL	TP_TRANSPORTER: inhibition of DNP-SG uptake in bile canalicular membrane vesicles from SD rat	F	5.66	pKi	2180	nM	Ki	Drug Metabol Pharmacokin (2002) 17: 23-33 [PMID:15618649]
Solute carrier organic anion transporter family member 1A1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1781859] [UniProtKB: P46720]
ChEMBL	TP_TRANSPORTER: inhibition of Enalapril uptake in Oatp1-expressing HeLa cells	F	5.7	pKi	1980	nM	Ki	Hepatology (1998) 28: 1341-1346 [PMID:9794920]
Solute carrier organic anion transporter family member 1A3 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073707] [UniProtKB: P70502]
ChEMBL	TP_TRANSPORTER: inhibition of MTX uptake in OAT-K1-expressing MDCK cells	F	4.68	pKi	21000	nM	Ki	J Pharmacol Exp Ther (2000) 293: 1034-1039 [PMID:10869408]
OATP1B1/Solute carrier organic anion transporter family member 1B1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1697668] [GtoPdb: 1220] [UniProtKB: Q9Y6L6]
ChEMBL	TP_TRANSPORTER: inhibition of E217betaG uptake in OATP-C-expressing HEK293 cells	F	7.36	pKi	44	nM	Ki	Am J Physiol Gastrointest Liver Physiol (2000) 278: G156-G164 [PMID:10644574]
ChEMBL	TP_TRANSPORTER: inhibition of Phalloidin uptake (Phalloidin: 1 uM) in OATP-C-expressing HEK293 cells	F	7.3	pIC50	50	nM	IC50	Naunyn Schmiedebergs Arch Pharmacol (2003) 368: 415-420 [PMID:14530907]
OATP2A1/Solute carrier organic anion transporter family member 2A1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073680] [GtoPdb: 1223] [UniProtKB: Q00910]
ChEMBL	TP_TRANSPORTER: inhibition of PGF2alpha uptake in PGT-expressing HeLa cells	F	5.24	pKi	5800	nM	Ki	Science (1995) 268: 866-869 [PMID:7754369]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]