ChEMBL ligand: CHEMBL453904 (Bromosulfalein, Bromsulphthalein, Bromthalein, Bsp sodium, Hepartest, Hepatestabrome, Hepatosulfalein, Sodium Bromsulphalein, Sodium bromsulphthalein, Sulfobromophthalein, Sulfobromophthalein sodium, Sulfobromopthalein sodium, Sulfobromphthalein sodium, Sulphobromophthalein)
Sodium/bile acid and sulphated solute cotransporter 1/Bile acid transporter in Human [ChEMBL: CHEMBL5287] [GtoPdb: 959] [UniProtKB: Q14973] There should be some charts here, you may need to enable JavaScript!
ABCC2/Canalicular multispecific organic anion transporter 1 in Rat [ChEMBL: CHEMBL2073676] [GtoPdb: 780] [UniProtKB: Q63120] There should be some charts here, you may need to enable JavaScript!
Solute carrier organic anion transporter family member 1A1 in Rat [ChEMBL: CHEMBL1781859] [UniProtKB: P46720] There should be some charts here, you may need to enable JavaScript!
Solute carrier organic anion transporter family member 1A3 in Rat [ChEMBL: CHEMBL2073707] [UniProtKB: P70502] There should be some charts here, you may need to enable JavaScript!
OATP1B1/Solute carrier organic anion transporter family member 1B1 in Human [ChEMBL: CHEMBL1697668] [GtoPdb: 1220] [UniProtKB: Q9Y6L6] There should be some charts here, you may need to enable JavaScript!
OATP2A1/Solute carrier organic anion transporter family member 2A1 in Rat [ChEMBL: CHEMBL2073680] [GtoPdb: 1223] [UniProtKB: Q00910] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Sodium/bile acid and sulphated solute cotransporter 1/Bile acid transporter in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5287] [GtoPdb: 959] [UniProtKB: Q14973]
ChEMBL	TP_TRANSPORTER: inhibition of Taurocholate uptake in NTCP-expressing HeLa cells	F	5.14	pIC50	7300	nM	IC50	J Pharmacol Exp Ther (1999) 291: 1204-1209 [PMID:10565843]
ABCC2/Canalicular multispecific organic anion transporter 1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073676] [GtoPdb: 780] [UniProtKB: Q63120]
ChEMBL	TP_TRANSPORTER: inhibition of SN-38 uptake in bile canalicular membrane vesicles from SD rat	F	5.54	pKi	2870	nM	Ki	Drug Metabol Pharmacokin (2002) 17: 23-33 [PMID:15618649]
ChEMBL	TP_TRANSPORTER: inhibition of DNP-SG uptake in bile canalicular membrane vesicles from SD rat	F	5.66	pKi	2180	nM	Ki	Drug Metabol Pharmacokin (2002) 17: 23-33 [PMID:15618649]
Solute carrier organic anion transporter family member 1A1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1781859] [UniProtKB: P46720]
ChEMBL	TP_TRANSPORTER: inhibition of Enalapril uptake in Oatp1-expressing HeLa cells	F	5.7	pKi	1980	nM	Ki	Hepatology (1998) 28: 1341-1346 [PMID:9794920]
Solute carrier organic anion transporter family member 1A3 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073707] [UniProtKB: P70502]
ChEMBL	TP_TRANSPORTER: inhibition of MTX uptake in OAT-K1-expressing MDCK cells	F	4.68	pKi	21000	nM	Ki	J Pharmacol Exp Ther (2000) 293: 1034-1039 [PMID:10869408]
OATP1B1/Solute carrier organic anion transporter family member 1B1 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1697668] [GtoPdb: 1220] [UniProtKB: Q9Y6L6]
ChEMBL	TP_TRANSPORTER: inhibition of E217betaG uptake in OATP-C-expressing HEK293 cells	F	7.36	pKi	44	nM	Ki	Am J Physiol Gastrointest Liver Physiol (2000) 278: G156-G164 [PMID:10644574]
ChEMBL	TP_TRANSPORTER: inhibition of Phalloidin uptake (Phalloidin: 1 uM) in OATP-C-expressing HEK293 cells	F	7.3	pIC50	50	nM	IC50	Naunyn Schmiedebergs Arch Pharmacol (2003) 368: 415-420 [PMID:14530907]
OATP2A1/Solute carrier organic anion transporter family member 2A1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073680] [GtoPdb: 1223] [UniProtKB: Q00910]
ChEMBL	TP_TRANSPORTER: inhibition of PGF2alpha uptake in PGT-expressing HeLa cells	F	5.24	pKi	5800	nM	Ki	Science (1995) 268: 866-869 [PMID:7754369]

ChEMBL data shown on this page come from version 33:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]