[3H]ZM 241385 [Ligand Id: 455] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1628684 (ZM-241385)
  • A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
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  • A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
A2A receptor in Human [GtoPdb: 19] [UniProtKB: P29274]
GtoPdb - - 9.1 pKd 0.8 nM Kd Eur J Pharmacol (2001) 411: 205-10 [PMID:11164377];
Biochem Pharmacol (2000) 60: 661-8 [PMID:10927024]
A2B receptor in Human [GtoPdb: 20] [UniProtKB: P29275]
GtoPdb - - 7.9 pKd - - - Biochem Pharmacol (2001) 62: 1163-73 [PMID:11705449];
Biochem Pharmacol (2004) 68: 305-12 [PMID:15194002];
Drug Des Discov (1999) 16: 217-26 [PMID:10624567]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]