thymine [Ligand Id: 4581] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL993 (Thymine)
  • ATPase family AAA domain containing 2/ATPase family AAA domain-containing protein 2 in Human [ChEMBL: CHEMBL2150837] [GtoPdb: 2719] [UniProtKB: Q6PL18]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ATPase family AAA domain containing 2/ATPase family AAA domain-containing protein 2 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2150837] [GtoPdb: 2719] [UniProtKB: Q6PL18]
ChEMBL Binding affinity to recombinant human ATAD2 (982 to 1108 amino acids) bromodomain radiolabelled at methyl groups of leucine, valine, isoleucine, methionine expressed in Escherichia coli BL21 (DE3) by NMR titration B 2 pKd 10000000 nM Kd MedChemComm (2014) 5: 1843-1848

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]