Click here for a description of the charts and data table
Please tell us if you are using this feature and what you think!
ChEMBL ligand: CHEMBL305686 (3'-Deoxyadenosine, 9-cordyceposidoadenine, Cordycepin, Cordycepine, NSC-401022, NSC-63984) |
---|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
There should be some charts here, you may need to enable JavaScript!
|
DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
---|---|---|---|---|---|---|---|---|
A1 receptor/Adenosine A1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL318] [GtoPdb: 18] [UniProtKB: P25099] | ||||||||
ChEMBL | Affinity for the Adenosine A1 receptor in the presence of GTP (A1+GTP) by using [3H]-DPCPX as radioligand | B | 4.82 | pKi | 15200 | nM | Ki | J Med Chem (1995) 38: 4000-4006 [PMID:7562934] |
ChEMBL | Affinity for adenosine A1 receptor was determined, in the presence of GTP in rat brain cortex | B | 4.82 | pKi | 15200 | nM | Ki | J Med Chem (1997) 40: 3765-3772 [PMID:9371242] |
ChEMBL | Affinity for the Adenosine A1 receptor in the absence of GTP (A1-GTP) by using [3H]DPCPX as radioligand | B | 5.15 | pKi | 7120 | nM | Ki | J Med Chem (1995) 38: 4000-4006 [PMID:7562934] |
ChEMBL | Affinity for adenosine A1 receptor was determined, in the absence of GTP in rat cortical membrane. | B | 5.15 | pKi | 7120 | nM | Ki | J Med Chem (1997) 40: 3765-3772 [PMID:9371242] |
RNA-directed RNA polymerase in Hepacivirus hominis (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4296320] [UniProtKB: O39930] | ||||||||
ChEMBL | Inhibition HCV NS5B-mediated RNA synthesis | F | 4.66 | pIC50 | 22000 | nM | IC50 | J Med Chem (2004) 47: 2283-2295 [PMID:15084127] |
ChEMBL | Inhibition HCV RNA replication | F | 4.34 | pEC50 | 46000 | nM | EC50 | J Med Chem (2004) 47: 2283-2295 [PMID:15084127] |
Sterol 14-alpha demethylase in Trypanosoma cruzi (strain CL Brener) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075110] [UniProtKB: Q7Z1V1] | ||||||||
ChEMBL | GSK_TCAKS: pIC50 CYP51 from Trypanosoma cruzi. | F | 4 | pIC50 | >100000 | nM | IC50 | GSK Tres Cantos Anti-Kinetoplastid Screening (TCAKS) Data. |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]