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ChEMBL ligand: CHEMBL1604 (Anspor, Cefradine, Cefradine hydrate, Cephradine, Cephradine anhydrous, Cephradine hydrate, Cephradine, unspecified hydrate, Ecosporina, Nicef, NSC-756672, SK-D-39304, SK&F D-39304, SQ 11436, SQ-11436, SQ-22022, SQ 22022 [DIHYDRATE], Velosef, Velosef '125', Velosef '250', Velosef '500') |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Peptide transporter 2/Oligopeptide transporter, kidney isoform in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3325] [GtoPdb: 985] [UniProtKB: Q63424] | ||||||||
ChEMBL | TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in SKPT cells | F | 4.19 | pKi | 65000 | nM | Ki | Eur J Pharm Biopharm (2005) 59: 17-24 [PMID:15567297] |
ChEMBL | TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells | F | 4.33 | pKi | 47000 | nM | Ki | Am J Physiol (1997) 273: F706-F711 [PMID:9374833] |
Peptide transporter 1/Oligopeptide transporter small intestine isoform in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4605] [GtoPdb: 984] [UniProtKB: P46059] | ||||||||
ChEMBL | TP_TRANSPORTER: inhibition of Gly-Sar uptake (pH6.0) in Caco-2 cells | F | 5.01 | pKi | 9800 | nM | Ki | Eur J Pharm Biopharm (2005) 59: 17-24 [PMID:15567297] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]