noradrenaline | Ligand Activity Charts | IUPHAR/BPS Guide to PHARMACOLOGY

Home
Ligands
noradrenaline
Ligand Activity Charts

noradrenaline [Ligand Id: 484] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL432
β₁-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588] There should be some charts here, you may need to enable JavaScript!
β₂-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550] There should be some charts here, you may need to enable JavaScript!
D₁ receptor in Human [GtoPdb: 214] [UniProtKB: P21728] There should be some charts here, you may need to enable JavaScript!
D₅ receptor in Human [GtoPdb: 218] [UniProtKB: P21918] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
β₁-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
GtoPdb	-	-	6	pKi	-	-	-	Proc Natl Acad Sci USA (1988) 85: 9494-8 [PMID:2849109]
β₂-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
GtoPdb	-	-	5.4	pKi	-	-	-	Mol Pharmacol (2004) 65: 1181-90 [PMID:15102946]
D₁ receptor in Human [GtoPdb: 214] [UniProtKB: P21728]
GtoPdb	-	-	4.3	pKi	-	-	-	Nature (1991) 350: 614-9 [PMID:1826762]
D₅ receptor in Human [GtoPdb: 218] [UniProtKB: P21918]
GtoPdb	-	-	4.9	pKi	-	-	-	Nature (1991) 350: 614-9 [PMID:1826762]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]