noradrenaline [Ligand Id: 484] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL432
  • β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
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  • β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
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  • D1 receptor in Human [GtoPdb: 214] [UniProtKB: P21728]
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  • D5 receptor in Human [GtoPdb: 218] [UniProtKB: P21918]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
GtoPdb - - 6 pKi - - - Proc Natl Acad Sci USA (1988) 85: 9494-8 [PMID:2849109]
β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
GtoPdb - - 5.4 pKi - - - Mol Pharmacol (2004) 65: 1181-90 [PMID:15102946]
D1 receptor in Human [GtoPdb: 214] [UniProtKB: P21728]
GtoPdb - - 4.3 pKi - - - Nature (1991) 350: 614-9 [PMID:1826762]
D5 receptor in Human [GtoPdb: 218] [UniProtKB: P21918]
GtoPdb - - 4.9 pKi - - - Nature (1991) 350: 614-9 [PMID:1826762]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]