linaclotide [Ligand Id: 5017] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Guanylyl cyclase-C in Human [GtoPdb: 1750] [UniProtKB: P25092] | ||||||||
| GtoPdb | Competitive-inhibition of [125I]-STa binding to T84 colorectal carcinoma cells | - | 8.91 | pKi | 1.24 | nM | Ki |
Curr Opin Mol Ther (2007) 9: 403-10 [PMID:17694454]; Eur J Pharmacol (2010) 649: 328-35 [PMID:20863829] |
| Guanylyl cyclase-C in Rat [GtoPdb: 1750] [UniProtKB: P23897] | ||||||||
| GtoPdb | Competitive-inhibition of [125I]-STa binding to rat intestinal mucosa | - | 8.38 | pKi | 4.2 | nM | Ki | Eur J Pharmacol (2010) 649: 328-35 [PMID:20863829] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
