(±)-adrenaline [Ligand Id: 509] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1740 (Vaponefrin, Racepinefrine, Racepinephrine)
  • α2B-adrenoceptor in Human [GtoPdb: 26] [UniProtKB: P18089]
  • This target only has 1 pki data point
  • 6.2
1 CHEMBL1740_lig_chart_1 α2B-adrenoceptor Human
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  • α2C-adrenoceptor in Human [GtoPdb: 27] [UniProtKB: P18825]
  • This target only has 1 pki data point
  • 6.2
2 CHEMBL1740_lig_chart_2 α2C-adrenoceptor Human
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  • β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
  • This target only has 1 pki data point
  • 6
3 CHEMBL1740_lig_chart_3 β1-adrenoceptor Human
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  • β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
  • β3-adrenoceptor in Mouse [GtoPdb: 30] [UniProtKB: P25962]
  • β3-adrenoceptor in Rat [GtoPdb: 30] [UniProtKB: P26255]
  • 5.3
4 CHEMBL1740_lig_chart_4 β3-adrenoceptor HumanMouseRat
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
α2B-adrenoceptor in Human [GtoPdb: 26] [UniProtKB: P18089]
GtoPdb - - 6.2 pKi - - - Biochem Pharmacol (1998) 55: 1035-43 [PMID:9605427]
α2C-adrenoceptor in Human [GtoPdb: 27] [UniProtKB: P18825]
GtoPdb - - 6.2 pKi - - - Biochem Pharmacol (1998) 55: 1035-43 [PMID:9605427]
β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
GtoPdb - - 6 pKi - - - Proc Natl Acad Sci USA (1988) 85: 9494-8 [PMID:2849109]
β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
GtoPdb - - 4.7 pKi - - - Eur J Pharmacol (1995) 291: 359-66 [PMID:8719421];
Mol Pharmacol (1993) 44: 1094-104 [PMID:7903415];
Naunyn Schmiedebergs Arch Pharmacol (2004) 369: 151-9 [PMID:14730417]
β3-adrenoceptor in Mouse [GtoPdb: 30] [UniProtKB: P25962]
GtoPdb - - 5.3 pKi - - - Eur J Pharmacol (1995) 291: 359-66 [PMID:8719421]
β3-adrenoceptor in Rat [GtoPdb: 30] [UniProtKB: P26255]
GtoPdb - - 5.3 pKi - - - Eur J Pharmacol (1995) 291: 359-66 [PMID:8719421]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]