2'-deoxyadenosine [Ligand Id: 5109] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL449329 (2'-Deoxyadenosine) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| A1 receptor/Adenosine A1 receptor in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL318] [GtoPdb: 18] [UniProtKB: P25099] | ||||||||
| ChEMBL | Affinity for the Adenosine A1 receptor in the presence of GTP (A1+GTP) by using [3H]-DPCPX as radioligand | B | 4.63 | pKi | 23300 | nM | Ki | J Med Chem (1995) 38: 4000-4006 [PMID:7562934] |
| adenylyl cyclase 5/Adenylate cyclase type V in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2880] [GtoPdb: 1282] [UniProtKB: Q04400] | ||||||||
| ChEMBL | Compound was evaluated for inhibition of adenylate cyclase from rat brain | B | 4.82 | pIC50 | 15000 | nM | IC50 | J Med Chem (2004) 47: 1207-1213 [PMID:14971900] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
